Abudu O O, Sofola O A
Int J Gynaecol Obstet. 1985 Apr;23(2):137-42. doi: 10.1016/0020-7292(85)90059-1.
Plasma volume was measured in 10 non-pregnant, healthy nulliparous Nigerian and 30 normal primigravid Nigerians at various times of gestation by the Evans blue dye dilution technique. The mean plasma volume of 2098 ml for the non-pregnant Nigerians was statistically different (P less than 0.001) from values in non-pregnant caucasian primigravidae of comparable status. A mean maximum plasma volume increase of 1387 ml above non-pregnant value was found. Essentially, pregnancy imposed a much higher physiological load on Nigerian primigravidae compared to caucasian primigravidae. There was a significant negative correlation between plasma volume and packed cell volume (PCV) in pregnancy (r = -0.51, P less than 0.001), which may be related to excessive hemodilution in the primigravid Nigerian. Differences found may be due to geographical and/or racial factors.
采用伊文思蓝染料稀释技术，在妊娠不同阶段对10名未怀孕的健康尼日利亚未育女性和30名正常初孕尼日利亚女性进行血浆容量测量。未怀孕尼日利亚女性的平均血浆容量为2098毫升，与同等状态的未怀孕白种人初孕妇相比，差异具有统计学意义（P<0.001）。发现血浆容量较未怀孕时平均最大增加量为1387毫升。从本质上讲，与白种人初孕妇相比，怀孕给尼日利亚初孕妇带来了更高的生理负担。妊娠期间血浆容量与红细胞压积（PCV）之间存在显著负相关（r = -0.51，P<0.001），这可能与尼日利亚初孕妇过度血液稀释有关。所发现的差异可能是由于地理和/或种族因素。
