尼日利亚初产妇正常血清铁蛋白及其他血液学参数的系列研究

Serial serum ferritin and other hematological parameters in normal Nigerian primigravidae.

作者信息

Abudu O O, Macaulay K, Oluboyede O A

机构信息

Department of Obstetrics & Gynaecology, College of Medicine, University of Lagos, Nigeria.

出版信息

Int J Gynaecol Obstet. 1988 Feb;26(1):33-9. doi: 10.1016/0020-7292(88)90193-2.

DOI:10.1016/0020-7292(88)90193-2

PMID:2892735

Abstract

Serial hematological indices using Coulter Counter and serum ferritin using radioimmunoassay techniques were determined in 20 healthy Nigerian primigravidae with hemoglobin genotype AA. PCV fell significantly (P less than 0.001) to a minimum value at 28 weeks that was 6% lower than the mean value at 8 weeks postpartum. PCV at 36 weeks was still significantly (P less than 0.001) lower than the post partum value. There was an insignificant but progressive increase in MCV values throughout pregnancy. Changes in MCH and MCHC were insignificant. Ferritin levels in both the non-pregnant and pregnant subjects were high and probably reflected the high iron content of Nigerian foods. Though the cord serum ferritin level was significantly higher (P less than 0.001) than maternal ferritin at delivery there was no significant correlation between the two.

摘要

对20名血红蛋白基因型为AA的健康尼日利亚初产妇进行了使用库尔特计数器的系列血液学指标测定以及使用放射免疫测定技术的血清铁蛋白测定。红细胞压积（PCV）在28周时显著下降（P<0.001）至最低值，比产后8周的平均值低6%。36周时的红细胞压积仍显著低于产后值（P<0.001）。整个孕期平均红细胞体积（MCV）值有不显著但呈进行性的增加。平均红细胞血红蛋白含量（MCH）和平均红细胞血红蛋白浓度（MCHC）的变化不显著。非孕期和孕期受试者的铁蛋白水平都很高，这可能反映了尼日利亚食物中铁含量高。尽管脐血血清铁蛋白水平在分娩时显著高于母体铁蛋白（P<0.001），但两者之间无显著相关性。