Cheesbrough J S, Finch R G
J Hosp Infect. 1985 Jun;6(2):201-8.
A randomized prospective study was conducted to assess the effect of inserting a bacteria-retaining filter into the side-port of 'Venflon' cannulae. Observations were made on 109 cannulae with filters and 100 without. Although there was a trend towards a reduced rate of side-port colonization in the cannulae with filters this was not paralleled by any reduction in the incidence of local inflammation or colonization of the intravascular segment (IVS) of the cannula. Of the 37 cannulae with positive cultures from the skin at the cannula insertion site 22 yielded indistinguishable bacteria from the IVS, while only three of the 25 positive side-port cultures were similarly associated. It is concluded that in the majority of cases, organisms isolated from the IVS originate on the skin and that organisms introduced via the side-port rarely lead to IVS colonization.
进行了一项随机前瞻性研究，以评估在“Venflon”套管侧端口插入细菌保留过滤器的效果。对109个带有过滤器的套管和100个没有过滤器的套管进行了观察。尽管带有过滤器的套管侧端口定植率有降低的趋势，但局部炎症发生率或套管血管内段（IVS）定植率并未相应降低。在37个插管部位皮肤培养阳性的套管中，22个培养出与IVS难以区分的细菌，而25个侧端口培养阳性的套管中只有3个有类似关联。得出的结论是，在大多数情况下，从IVS分离出的微生物起源于皮肤，通过侧端口引入的微生物很少导致IVS定植。
