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泪溢手术后患者报告结局及生活质量改善情况的评估

Assessment of patient-reported outcome and quality of life improvement following surgery for epiphora.

作者信息

Sipkova Z, Vonica O, Olurin O, Obi E E, Pearson A R

机构信息

Department of Ophthalmology, Royal Berkshire Hospital, Reading, UK.

Department of Ophthalmology, King Edward VII Hospital, Windsor, UK.

出版信息

Eye (Lond). 2017 Dec;31(12):1664-1671. doi: 10.1038/eye.2017.120. Epub 2017 Jun 16.

Abstract

PurposeTo assess and compare the subjective improvement in symptoms and quality of life in adult patients who underwent commonly performed oculoplastic surgical interventions to treat epiphora.Materials and methodsA prospective study was undertaken involving all adult patients undergoing dacryocystorhinostomy (DCR), lid tightening (lateral tarsal strip or lateral wedge resection), and punctoplasty surgery at our institution. We assessed severity of epiphora preoperatively using the Munk score. At 3 months postoperatively, all patients were sent postal questionnaires comprising of Munk score, 'social impact score' from validated Lac-Q questionnaire ranging from 0 (no impact) to 5 (maximal negative impact) and Glasgow Benefit Inventory (GBI) score, ranging from -100 (maximal detriment) to +100 (maximal benefit).ResultsA total of 134 questionnaires were sent with an overall response rate of 74.6%. For the purpose of data analysis, patients were divided into four groups: DCR, lid tightening, punctoplasty, and combined group (lid tightening plus punctoplasty). There was statistically significant improvement in subjective epiphora postoperatively, as assessed by Munk score (P<0.001) in all groups. The total GBI scores were +42.67 (95% CI: 33.42-51.91) for DCR, +19.65 (95% CI: 10.33-28.97) for lid tightening, +16.06 (95% CI: 2.65-29.48) for punctoplasty, and +26.53 (95% CI: 13.15-39.90) for the combined group, demonstrating a positive change in health status for all groups. There was negative correlation between total GBI and post-operative Munk scores (r=-0.58, P<0.001), and positive correlation between Lac-Q and Munk scores (r=0.65, P<0.001).ConclusionPatients derived significant improvement in symptoms and health-related quality of life benefit following all surgical interventions for epiphora.

摘要

目的

评估并比较接受常见眼部整形手术干预治疗溢泪症的成年患者症状和生活质量的主观改善情况。

材料与方法

进行一项前瞻性研究,纳入在本机构接受泪囊鼻腔吻合术(DCR)、眼睑收紧术(外侧睑板条或外侧楔形切除术)和泪点成形术的所有成年患者。我们术前使用蒙克评分评估溢泪严重程度。术后3个月,向所有患者发送邮政问卷,问卷包括蒙克评分、经过验证的拉克-Q问卷中的“社会影响评分”(范围从0分(无影响)到5分(最大负面影响))以及格拉斯哥效益量表(GBI)评分(范围从-100分(最大损害)到+100分(最大益处))。

结果

共发送134份问卷,总体回复率为74.6%。为进行数据分析,将患者分为四组:DCR组、眼睑收紧组、泪点成形术组和联合组(眼睑收紧术加泪点成形术)。所有组术后主观溢泪情况经蒙克评分评估有统计学显著改善(P<0.001)。DCR组的GBI总评分为+42.67(95%置信区间:33.42 - 51.91),眼睑收紧组为+19.65(95%置信区间:10.33 - 28.97),泪点成形术组为+16.06(95%置信区间:2.65 - 29.48),联合组为+26.53(95%置信区间:13.15 - 39.90),表明所有组的健康状况都有积极变化。GBI总分与术后蒙克评分呈负相关(r = -0.58,P<0.001),拉克-Q评分与蒙克评分呈正相关(r = 0.65,P<0.001)。

结论

所有溢泪症手术干预后,患者的症状及与健康相关的生活质量均有显著改善。

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