Department of Ophthalmology, Republic of Turkey Health Sciences University Izmir Tepecik Training and Research Hospital, Izmir, Turkey.
Int Ophthalmol. 2024 Feb 21;44(1):105. doi: 10.1007/s10792-024-03038-4.
This study aims to investigate the effects of external dacryocystorhinostomy (DCR) surgery on tear meniscus parameters and assess its relationship with improvements in quality of life (QoL) in patients with nasolacrimal duct obstruction (NLDO).
This prospective study included 30 patients diagnosed with NLDO who underwent external DCR surgery. Tear meniscus (TM) parameters, including height, depth and area, were measured using anterior segment optical coherence tomography. Lacrimal symptom questionnaire (LacQ), Munk scores and Glasgow benefit inventories (GBI) were collected. Statistical analysis was performed to evaluate the correlation between tear meniscus changes and improvements in QoL.
TM height, depth and area decreased from preoperative median measurements (0.09 mm, 0.37 mm, 0.56 mm) to postoperative median measurements (0.03 mm, 0.21 mm, 0.30 mm) (p < 0.001). Lacrimal symptom scores and Munk scores showed a significant improvement at 3-month postoperatively (p < 0.001). The GBI scores also demonstrated a significant improvement, indicating a positive impact on the patients' QoL. (p < 0.001). A statistically significant correlation was found between the change in TM parameters and LacQ lacrimal symptom scores.
External DCR surgery leads to significant improvements in tear meniscus parameters and quality of life outcomes in patients with NLDO. The decreased in TM height and TM area indicates improved tear film dynamics and decreased tear volume, which positively impact the patients' ocular comfort and overall well-being. This study highlights the importance of tear meniscus evaluation as a potential market for assessing the success of DCR surgery and its impact on patients' QoL.
本研究旨在探讨外路泪囊鼻腔吻合术(DCR)对外泪膜月牙参数的影响,并评估其与鼻泪管阻塞(NLDO)患者生活质量(QoL)改善的关系。
本前瞻性研究纳入了 30 例经诊断为 NLDO 并接受外路 DCR 手术的患者。使用眼前节光学相干断层扫描(OCT)测量泪膜月牙(TM)参数,包括高度、深度和面积。收集泪液症状问卷(LacQ)、Munk 评分和格拉斯哥效益量表(GBI)。进行统计分析以评估泪膜月牙变化与 QoL 改善之间的相关性。
TM 高度、深度和面积从术前中位数测量值(0.09 毫米、0.37 毫米、0.56 毫米)分别降至术后中位数测量值(0.03 毫米、0.21 毫米、0.30 毫米)(p < 0.001)。术后 3 个月时,泪液症状评分和 Munk 评分均显著改善(p < 0.001)。GBI 评分也显著改善,表明对患者 QoL 有积极影响(p < 0.001)。TM 参数变化与 LacQ 泪液症状评分之间存在显著相关性。
外路 DCR 手术可显著改善 NLDO 患者的 TM 参数和生活质量。TM 高度和 TM 面积的降低表明泪膜动力学改善,泪液量减少,这对患者的眼部舒适度和整体幸福感产生积极影响。本研究强调了评估 TM 作为评估 DCR 手术成功率及其对患者 QoL 影响的潜在市场的重要性。