Dosokey Eslam M G, Brady Justin T, Neupane Ruel, Jabir Murad A, Stein Sharon L, Reynolds Harry L, Delaney Conor P, Steele Scott R
Department of Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH, USA; Department of Surgical Oncology, SECI, Assiut University, Assiut, Egypt.
Department of Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Am J Surg. 2017 Sep;214(3):416-420. doi: 10.1016/j.amjsurg.2017.05.012. Epub 2017 Jun 8.
Abdominoperineal Resection (APR) remains an important option for patients with advanced rectal cancer though some may require multivisceral resection (MVR) in addition to APR. We hypothesized that oncological outcomes would be worse with MVR.
A retrospective review from 2006 to 2015 of 161 patients undergoing APR or MVR for rectal cancer, of whom 118 underwent curative APR or APR with MVR. Perioperative, oncologic and survival metrics were evaluated.
There were 82 patients who underwent APR and 36 who underwent MVR. Surgical approach and incidence of complications were similar (All P > 0.05). There was 1 local recurrence in each of the APR and MVR groups at a mean follow-up of 34 and 32 months, respectively. Distant recurrences occurred in 3 APR patients and 4 MVR patients.
APR and APR with MVR can be performed with comparable morbidity and oncologic outcomes.
腹会阴联合切除术（APR）仍然是晚期直肠癌患者的重要选择，尽管有些患者除了APR外可能还需要多脏器切除术（MVR）。我们假设MVR的肿瘤学结局会更差。
对2006年至2015年期间161例因直肠癌接受APR或MVR的患者进行回顾性研究，其中118例接受了根治性APR或联合MVR的APR。评估围手术期、肿瘤学和生存指标。
82例患者接受了APR，36例接受了MVR。手术方式和并发症发生率相似（所有P>0.05）。APR组和MVR组各有1例局部复发，平均随访时间分别为34个月和32个月。3例APR患者和4例MVR患者发生远处复发。
APR以及联合MVR的APR手术在发病率和肿瘤学结局方面具有可比性。
