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未诊断出的阻塞性睡眠呼吸暂停的概率与不良肺部事件以及使用鞘内阿片类药物进行髋关节和膝关节置换术的住院时间均无相关性。

Probability of Undiagnosed Obstructive Sleep Apnea Does Not Correlate With Adverse Pulmonary Events nor Length of Stay in Hip and Knee Arthroplasty Using Intrathecal Opioid.

作者信息

Thompson Matthew J, Clinger Bryce N, Simonds Robert M, Hochheimer Camille J, Lahaye Laura A, Golladay Gregory J

机构信息

Department of Orthopaedic Surgery, Virginia Commonwealth University Medical Center, Richmond, Virginia.

School of Medicine, Virginia Commonwealth University Medical Center, Richmond, Virginia.

出版信息

J Arthroplasty. 2017 Sep;32(9):2676-2679. doi: 10.1016/j.arth.2017.02.043. Epub 2017 Apr 14.

DOI:10.1016/j.arth.2017.02.043
PMID:28622969
Abstract

BACKGROUND

Recent emphasis on bundled payments and outcomes tracking has increased the focus on preoperative optimization in patients undergoing elective lower extremity arthroplasty. Since patients with obstructive sleep apnea (OSA) have an increased risk of adverse perioperative pulmonary events, screening for undiagnosed OSA is sometimes included as part of preoperative risk assessment. However, there are limited data regarding quantification of OSA risk in lower extremity arthroplasty patients, and little is known about the utility of quantitative OSA screening and the risk of pulmonary complications in hip and knee arthroplasty patients who receive intrathecal morphine anesthetic.

METHODS

A retrospective review of 990 patients at a tertiary care, urban academic medical center who underwent lower extremity arthroplasty with a multimodal pain regimen including intrathecal morphine anesthesia, comparing the rate of pulmonary complications and length of stay between patients previously diagnosed with OSA and those identified as low, moderate, and high risk of undiagnosed OSA established by screening with the STOP-BANG questionnaire in the preoperative setting.

RESULTS

Using logistic regression and adjusting for age, gender, and body mass index, the results suggested the rate of complications was not different across the sleep apnea risk groups (P = .4024). In addition, linear regression suggested length of stay did not differ significantly by sleep apnea risk group (P = .2823).

CONCLUSION

In patients receiving intrathecal morphine as part of a multimodal pain regimen undergoing hip or knee arthroplasty, neither risk of adverse pulmonary events nor length of stay appeared to correlate with preoperative risk of undiagnosed OSA.

摘要

背景

近期对捆绑支付和结果跟踪的重视增加了对接受择期下肢关节置换术患者术前优化的关注。由于阻塞性睡眠呼吸暂停(OSA)患者围手术期肺部不良事件风险增加,未确诊OSA的筛查有时被纳入术前风险评估的一部分。然而,关于下肢关节置换术患者OSA风险量化的数据有限,对于接受鞘内吗啡麻醉的髋膝关节置换术患者进行定量OSA筛查的效用及肺部并发症风险知之甚少。

方法

对一家城市学术三级医疗中心的990例行下肢关节置换术并采用包括鞘内吗啡麻醉在内的多模式镇痛方案的患者进行回顾性研究,比较术前已确诊OSA的患者与术前通过STOP - BANG问卷筛查确定为未确诊OSA低、中、高风险患者的肺部并发症发生率和住院时间。

结果

使用逻辑回归并对年龄、性别和体重指数进行校正后,结果表明各睡眠呼吸暂停风险组的并发症发生率无差异(P = 0.4024)。此外,线性回归表明住院时间在各睡眠呼吸暂停风险组之间无显著差异(P = 0.2823)。

结论

在接受鞘内吗啡作为多模式镇痛方案一部分的髋膝关节置换术患者中,不良肺部事件风险和住院时间似乎均与术前未确诊OSA的风险无关。

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