• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[无可用内容]。

[Not Available].

作者信息

Córcoles David, Malagón Angeles, Bellsolà Magdalena, Gonzalez Ana, Cortizo Romina, Leon Jordi, Bulbena Antoni, Pérez Victor, Martín Luis M

机构信息

Institut de Neuropsiquiatria i Addiccions, Hospital del Mar, Barcelona, España; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Barcelona, España.

Institut de Neuropsiquiatria i Addiccions, Hospital del Mar, Barcelona, España.

出版信息

Aten Primaria. 2018 May;50(5):267-273. doi: 10.1016/j.aprim.2017.01.015. Epub 2017 Jun 13.

DOI:10.1016/j.aprim.2017.01.015
PMID:28623009
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6836988/
Abstract

OBJECTIVE

The aim of the study was to evaluate whether the neuropsychiatric symptoms interfere with cognitive impairment detection in primary care and to describe which of them generate more confusion.

DESIGN

Descriptive and observational study.

LOCATION

Mobile psychiatric unit in collaboration with primary healthcare centers in Barcelona.

PARTICIPANTS

A total of 104 patients over 65years referred to mobile psychiatric unit from primary healthcare clinicians suspecting mental disease.

MAIN MEASUREMENTS

All patients received a DSM-IV-TR diagnosis. We included in the study the Mini Mental State Examination (MMSE), Neuropsichiatric Inventory, Severe Psychiatric Illness scale, Global Assessment of Functioning, Clinical Global Impression and Word Health Organisation Dissability Assessment Schedule.

RESULTS

55.8% of patients referred from primary care had altered MMSE score. Neuropsychiatric symptoms more frequently associated with suspected cognitive impairment were delusions, hallucinations, agitation, disinhibition, irritability and purposeless motor behavior.

CONCLUSIONS

When psychiatric symptoms of Severe Mental Disorder (SMD) are detected in elderly individuals with no history of SMD, cognitive impairment should be suspected and a screening test be done.

摘要

目的

本研究旨在评估神经精神症状是否会干扰基层医疗中认知障碍的检测,并描述其中哪些症状会造成更多混淆。

设计

描述性观察研究。

地点

与巴塞罗那的基层医疗中心合作的流动精神科单位。

参与者

共有104名65岁以上的患者从基层医疗临床医生处转诊至流动精神科单位,这些临床医生怀疑患者患有精神疾病。

主要测量指标

所有患者均接受了DSM-IV-TR诊断。我们将简易精神状态检查表(MMSE)、神经精神科问卷、严重精神疾病量表、功能总体评估、临床总体印象和世界卫生组织残疾评估表纳入研究。

结果

从基层医疗转诊来的患者中,55.8%的患者MMSE评分有改变。与疑似认知障碍更常相关的神经精神症状是妄想、幻觉、激越、脱抑制、易激惹和无目的运动行为。

结论

当在无严重精神障碍(SMD)病史的老年人中检测到严重精神障碍的精神症状时,应怀疑存在认知障碍并进行筛查测试。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bf4/6836988/6fad32d424b9/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bf4/6836988/6fad32d424b9/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bf4/6836988/6fad32d424b9/fx1.jpg

相似文献

1
[Not Available].[无可用内容]。
Aten Primaria. 2018 May;50(5):267-273. doi: 10.1016/j.aprim.2017.01.015. Epub 2017 Jun 13.
2
Neuropsychiatric differences between Parkinson's disease with dementia and Alzheimer's disease.帕金森病伴发痴呆与阿尔茨海默病之间的神经精神差异
Int J Geriatr Psychiatry. 2001 Feb;16(2):184-91. doi: 10.1002/1099-1166(200102)16:2<184::aid-gps304>3.0.co;2-k.
3
[Neuropsychiatric features in Dementia with Lewy bodies and Alzheimer's disease].[路易体痴呆和阿尔茨海默病的神经精神特征]
No To Shinkei. 1998 Jan;50(1):45-9.
4
Effect of risperidone on behavioral and psychological symptoms and cognitive function in dementia.利培酮对痴呆患者行为和心理症状及认知功能的影响。
J Clin Psychiatry. 2001 Nov;62(11):894-900. doi: 10.4088/jcp.v62n1110.
5
The course of neuropsychiatric symptoms in dementia: a 3-year longitudinal study.痴呆患者神经精神症状的病程:一项 3 年的纵向研究。
J Am Med Dir Assoc. 2015 May 1;16(5):380-7. doi: 10.1016/j.jamda.2014.12.018. Epub 2015 Feb 14.
6
Agitation in Alzheimer's disease is a manifestation of frontal lobe dysfunction.阿尔茨海默病中的激越表现为额叶功能障碍。
Dement Geriatr Cogn Disord. 2004;17(1-2):14-20. doi: 10.1159/000074080. Epub 2003 Oct 13.
7
Risk factors for neuropsychiatric symptoms in dementia: the Cache County Study.痴呆症神经精神症状的风险因素:卡什县研究。
Int J Geriatr Psychiatry. 2006 Sep;21(9):824-30. doi: 10.1002/gps.1567.
8
The association between cognitive impairment and neuropsychiatric symptoms in patients with Parkinson's disease dementia.帕金森病痴呆患者认知障碍与神经精神症状的关系。
Int Psychogeriatr. 2012 Dec;24(12):1980-7. doi: 10.1017/S1041610212001317. Epub 2012 Jul 27.
9
Relationship between dementia severity and behavioural and psychological symptoms in early-onset Alzheimer's disease.早发性阿尔茨海默病中痴呆严重程度与行为和心理症状之间的关系。
Psychogeriatrics. 2015 Dec;15(4):242-7. doi: 10.1111/psyg.12108. Epub 2015 Mar 3.
10
Delusions in Patients with Alzheimer's Disease: A Multidimensional Approach.阿尔茨海默病患者的妄想:一种多维研究方法。
J Alzheimers Dis. 2016;51(2):427-37. doi: 10.3233/JAD-150944.

引用本文的文献

1
Diagnosing dementia and cognitive dysfunction in the elderly in primary health care: A systematic review.基层医疗保健中老年人痴呆症和认知功能障碍的诊断:一项系统综述。
Dement Neuropsychol. 2019 Apr-Jun;13(2):144-153. doi: 10.1590/1980-57642018dn13-020002.

本文引用的文献

1
Activities of daily living and quality of life across different stages of dementia: a UK study.痴呆症不同阶段的日常生活活动与生活质量:一项英国研究。
Aging Ment Health. 2015 Jan;19(1):63-71. doi: 10.1080/13607863.2014.915920. Epub 2014 May 15.
2
[Psychological and behavioural symptoms of dementia: prevention, diagnosis and treatment].[痴呆症的心理和行为症状:预防、诊断与治疗]
Rev Neurol. 2012 Nov 16;55(10):598-608.
3
[Can dementia be diagnosed in primary care?].[痴呆症能否在初级保健中被诊断出来?]
Aten Primaria. 2011 Jul;43(7):377-84. doi: 10.1016/j.aprim.2010.09.004. Epub 2011 Feb 19.
4
Neuropsychiatric symptoms and syndromes in a large cohort of newly diagnosed, untreated patients with Alzheimer disease.阿尔茨海默病初诊未治疗患者大样本中神经精神症状和综合征。
Am J Geriatr Psychiatry. 2010 Nov;18(11):1026-35. doi: 10.1097/JGP.0b013e3181d6b68d.
5
Management of behavioral problems in Alzheimer's disease.阿尔茨海默病行为问题的管理。
Int Psychogeriatr. 2010 May;22(3):346-72. doi: 10.1017/S1041610209991505. Epub 2010 Jan 25.
6
Missed and delayed diagnosis of dementia in primary care: prevalence and contributing factors.初级保健中痴呆的漏诊和延迟诊断:患病率和相关因素。
Alzheimer Dis Assoc Disord. 2009 Oct-Dec;23(4):306-14. doi: 10.1097/WAD.0b013e3181a6bebc.
7
A systematic review of neuropsychiatric symptoms in mild cognitive impairment.轻度认知障碍患者的神经精神症状的系统评价。
J Alzheimers Dis. 2009;18(1):11-30. doi: 10.3233/JAD-2009-1120.
8
Prevalence of psychiatric symptoms and mental disorders detected in primary care in an elderly Spanish population. The PSICOTARD Study: preliminary findings.西班牙老年人群初级保健中检测到的精神症状和精神障碍患病率。PSICOTARD研究:初步结果。
Int J Geriatr Psychiatry. 2008 Sep;23(9):915-21. doi: 10.1002/gps.2004.
9
Neuropsychiatric manifestations in mild cognitive impairment: a systematic review of the literature.轻度认知障碍中的神经精神表现:文献系统综述
Dement Geriatr Cogn Disord. 2008;25(2):115-26. doi: 10.1159/000112509. Epub 2007 Dec 14.
10
Comparison of different clinical diagnostic criteria for depression in Alzheimer disease.阿尔茨海默病中抑郁症不同临床诊断标准的比较。
Am J Geriatr Psychiatry. 2006 Jul;14(7):589-97. doi: 10.1097/01.JGP.0000209396.15788.9d.