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依普利酮,治疗老问题的新方法:伴有顽固性黄斑水肿的色素性视网膜炎。

Eplerenone, a new treatment for an old problem: Retinitis pigmentosa with recalcitrant macular edema.

作者信息

Campos Polo R, Rubio Sánchez C, García Guisado D M, Díaz Luque M J

机构信息

Servicio de Oftalmología, Hospital Virgen del Puerto, Plasencia (Cáceres), España.

Servicio de Oftalmología, Hospital Virgen del Puerto, Plasencia (Cáceres), España.

出版信息

Arch Soc Esp Oftalmol (Engl Ed). 2018 Jan;93(1):38-41. doi: 10.1016/j.oftal.2017.05.002. Epub 2017 Jun 16.

DOI:10.1016/j.oftal.2017.05.002
PMID:28624313
Abstract

CASE REPORT

The case involves a 35-year-old man, with a history of retinitis pigmentosa, who presented with a bilateral cystoid macular oedema associated with bilateral epiretinal membrane, which was resistant to treatment with oral acetazolamide and intravitreal bevacizumab. The treatment with oral eplerenone was able to improve the visual acuity and macular thickness of this patient.

DISCUSSION

A variety of treatments have been proposed for the management of cystoid macular oedema, associated with retinitis pigmentosa, with variable results. The treatment with oral eplerenone might be a good option for the control of this condition.

摘要

病例报告

该病例为一名35岁男性,有视网膜色素变性病史,表现为双侧黄斑囊样水肿并伴有双侧视网膜前膜,对口服乙酰唑胺和玻璃体内注射贝伐单抗治疗无效。口服依普利酮治疗能够改善该患者的视力和黄斑厚度。

讨论

针对与视网膜色素变性相关的黄斑囊样水肿,已提出多种治疗方法,效果各异。口服依普利酮治疗可能是控制这种情况的一个好选择。

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