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慢性阻塞性肺疾病与勃起功能障碍之间是否存在关联?DECODED研究。

Does any association exist between Chronic Obstructive Pulmonary Disease and Erectile Dysfunction? The DECODED study.

作者信息

Dias M, Oliveira M J, Oliveira P, Ladeira I, Lima R, Guimarães M

机构信息

Pulmonology Department, Centro Hospitalar Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.

Pulmonology Department, Centro Hospitalar Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.

出版信息

Rev Port Pneumol (2006). 2017 Sep-Oct;23(5):259-265. doi: 10.1016/j.rppnen.2017.04.005. Epub 2017 Jun 16.

DOI:10.1016/j.rppnen.2017.04.005
PMID:28624321
Abstract

INTRODUCTION

Erectile dysfunction (ED) is the inability to achieve or maintain an erection for satisfactory sexual activity. Recent studies have shown an association between ED and chronic obstructive pulmonary disease (COPD). However, this issue is often ignored. We aimed to evaluate the ED prevalence in COPD patients and its risk factors and to study the impact of dyspnea in sexual activity.

METHODS

Cross-sectional study that included sexually active male patients with COPD. The International Index of Erectile Function (IIEF-5) questionnaire evaluated ED and the Respiratory Experiences with Sexuality Profile (RESP) was used to evaluate the impact of dyspnea on sexual activity. Risk factors for mild-moderate or moderate ED were determined using logistic regression.

RESULTS

84 patients were consecutively assessed for eligibility, 67 were included (median age: 65 years, 13% never-smokers). Twenty two percent had COPD 2011-GOLD A; 22% GOLD B, 14% GOLD C and 42% GOLD D. Fifty-eight patients (87%) had some degree of ED: 26 (45%) mild, 20 (34%) mild-moderate and 12 (21%) moderate ED. ED occurred in all GOLD stages of COPD, mainly in GOLD B and D stages. Higher CAT score was independently associated to mild-moderate/moderate ED. Most patients (85%) reported dyspnea during their sexual activity but 72% had never talked about it with their physician.

CONCLUSIONS

ED is highly prevalent among COPD patients and it is more severe in patients with higher CAT scores. Dyspnea affects their sexual activity but this is not a topic often discussed between patients and doctors, something which needs to be improved.

摘要

引言

勃起功能障碍(ED)是指无法勃起或维持勃起状态以进行满意的性活动。最近的研究表明,ED与慢性阻塞性肺疾病(COPD)之间存在关联。然而,这个问题常常被忽视。我们旨在评估COPD患者中ED的患病率及其危险因素,并研究呼吸困难对性活动的影响。

方法

对有性活动的男性COPD患者进行横断面研究。采用国际勃起功能指数(IIEF-5)问卷评估ED,并使用性活动呼吸体验量表(RESP)评估呼吸困难对性活动的影响。采用逻辑回归确定轻度-中度或中度ED的危险因素。

结果

连续评估84例患者的入选资格,67例被纳入研究(中位年龄:65岁,13%为从不吸烟者)。22%的患者为2011年全球慢性阻塞性肺疾病倡议(GOLD)A组;22%为GOLD B组,14%为GOLD C组,42%为GOLD D组。58例患者(87%)存在某种程度的ED:26例(45%)为轻度,20例(34%)为轻度-中度,12例(21%)为中度ED。ED在COPD的所有GOLD分期中均有发生,主要发生在GOLD B期和D期。较高的慢性阻塞性肺疾病评估测试(CAT)评分与轻度-中度/中度ED独立相关。大多数患者(85%)报告在性活动期间出现呼吸困难,但72%的患者从未与医生谈论过此事。

结论

ED在COPD患者中非常普遍,且在CAT评分较高的患者中更为严重。呼吸困难影响他们的性活动,但这并不是患者和医生经常讨论的话题,这一点需要改进。

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