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贝比格瓦伦西亚型皮肤敷贴器:剂量学研究及一种剂量学混合技术的应用

The Bebig Valencia-type skin applicators: Dosimetric study and implementation of a dosimetric hybrid technique.

作者信息

Anagnostopoulos Georgios, Andrássy Michael, Baltas Dimos

机构信息

Pi-Medical Ltd., Athens, Greece.

Eckert & Ziegler Bebig GmbH, Berlin, Germany.

出版信息

Brachytherapy. 2017 Sep-Oct;16(5):1044-1056. doi: 10.1016/j.brachy.2017.04.243. Epub 2017 Jun 16.

DOI:10.1016/j.brachy.2017.04.243
PMID:28624329
Abstract

PURPOSE

To determine the relative dose rate distribution in water for the Bebig 20 mm and 30 mm skin applicators and report results in a form suitable for potential clinical use. Results for both skin applicators are also provided in the form of a hybrid Task Group 43 (TG-43) dosimetry technique. Furthermore, the radiation leakage around both skin applicators from the radiation protection point of view and the impact of the geometrical source position uncertainties are studied and reported.

METHODS AND MATERIALS

Monte Carlo simulations were performed using the MCNP 6.1 general purpose code, which was benchmarked against published dosimetry data for the Bebig Ir2.A85-2 high-dose-rate iridium-192 source, as well as the dosimetry data for the two Elekta skin applicators. Both Bebig skin applicators were modeled, and the dose rate distributions in a water phantom were calculated. The dosimetric quantities derived according to a hybrid TG-43 dosimetry technique are provided with their corresponding uncertainty values. The air kerma rate in air was simulated in the vicinity of each skin applicator to assess the radiation leakage.

RESULTS AND CONCLUSIONS

Results from the Monte Carlo simulations of both skin applicators are presented in the form of figures and relative dose rate tables, and additionally with the aid of the quantities defined in the hybrid TG-43 dosimetry technique and their corresponding uncertainty values. Their output factors, flatness, and penumbra values were found comparable to the Elekta skin applicators. The radiation shielding was evaluated to be adequate. The effect of potential uncertainties in source positioning on dosimetry should be investigated as part of applicator commissioning.

摘要

目的

确定Bebig 20毫米和30毫米皮肤施源器在水中的相对剂量率分布,并以适合潜在临床应用的形式报告结果。两种皮肤施源器的结果也以混合任务组43(TG-43)剂量测定技术的形式提供。此外,从辐射防护的角度研究并报告了两种皮肤施源器周围的辐射泄漏以及几何源位置不确定性的影响。

方法和材料

使用MCNP 6.1通用代码进行蒙特卡罗模拟,该代码以已发表的Bebig Ir2.A85-2高剂量率铱-192源的剂量测定数据以及两种医科达皮肤施源器的剂量测定数据为基准。对两种Bebig皮肤施源器进行建模,并计算水模体中的剂量率分布。根据混合TG-43剂量测定技术得出的剂量学量及其相应的不确定度值也一并给出。在每个皮肤施源器附近模拟空气中的空气比释动能率,以评估辐射泄漏。

结果与结论

两种皮肤施源器的蒙特卡罗模拟结果以图表和相对剂量率表的形式呈现,此外还借助了混合TG-43剂量测定技术中定义的量及其相应的不确定度值。发现它们的输出因子、平坦度和半值层值与医科达皮肤施源器相当。评估得出辐射屏蔽是足够的。作为施源器调试的一部分,应研究源定位潜在不确定性对剂量测定的影响。

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