Division of Cardiovascular Medicine, Department of Internal Medicine, Electrophysiology Section, Ross Heart Hospital, The Wexner Medical Center at The Ohio State University Medical Center, Columbus, Ohio.
Department of Internal Medicine, The Wexner Medical Center at The Ohio State University Medical Center, Columbus, Ohio.
Heart Rhythm. 2017 Oct;14(10):1436-1439. doi: 10.1016/j.hrthm.2017.06.022. Epub 2017 Jun 15.
During early experience with subcutaneous implantable cardioverter-defibrillators (S-ICD), several patients had inappropriate shocks from T-wave oversensing (TWOS) during exercise. This prompted some operators to perform routine treadmill exercise tests after implantation of S-ICD to screen for TWOS. Meanwhile, improvements have been made in the detection algorithms by the manufacturer.
To assess whether routine treadmill exercise post S-ICD implantation is warranted.
Patients undergoing S-ICD implantation from October 2012 to December 2016 who were able to complete a treadmill exercise were included in the study. The amplitude of R and T waves as assessed by the device programmer at rest and peak exercise was calculated and incidence of TWOS recorded.
Eighty-seven patients with complete treadmill exercise test data were included in the final analysis. The majority of the patients received S-ICD for primary prevention. Nine percent of the included patients had hypertrophic obstructive cardiomyopathy. During treadmill exercise, there was significant increase in the heart rate from rest (77 ± 14 beats per minute) to peak exercise (133 ± 14 beats per minute; P < .0001). There was no significant difference between R-wave amplitude at rest (2 ± 0.77 mV) and peak exercise (1.88 ± 0.94 mV; P = .36). Similarly, there was no significant difference between T-wave amplitude at rest (0.27 ± 0.19 mV) and peak exercise (0.33 ± 0.23 mV; P = .06). The incidence of TWOS during exercise was zero.
With current screening and detection algorithms for S-ICD, routine treadmill exercise does not result in additional discrimination of patients susceptible to TWOS.
在皮下植入式心律转复除颤器(S-ICD)的早期应用中,一些患者在运动过程中因 T 波过感知(TWOS)而出现不适当的电击。这促使一些操作人员在植入 S-ICD 后进行常规跑步机运动测试,以筛查 TWOS。同时,制造商对检测算法进行了改进。
评估植入 S-ICD 后是否需要进行常规跑步机运动测试。
研究纳入了 2012 年 10 月至 2016 年 12 月期间接受 S-ICD 植入并能够完成跑步机运动的患者。通过设备程控器在休息和运动峰值时评估 R 波和 T 波的幅度,并记录 TWOS 的发生率。
最终有 87 例患者完成了完整的跑步机运动测试,纳入了最终分析。大多数患者因一级预防而接受 S-ICD 治疗。纳入患者中有 9%患有肥厚型梗阻性心肌病。在跑步机运动过程中,心率从休息时的 77±14 次/分显著增加至运动峰值时的 133±14 次/分(P<0.0001)。休息时 R 波幅度(2±0.77 mV)与运动峰值时(1.88±0.94 mV)无显著差异(P=0.36)。同样,休息时 T 波幅度(0.27±0.19 mV)与运动峰值时(0.33±0.23 mV)无显著差异(P=0.06)。运动过程中 TWOS 的发生率为零。
使用当前 S-ICD 的筛查和检测算法,常规跑步机运动并不能增加对易发生 TWOS 患者的区分度。