Office of the Clinical Director, National Institute of Mental Health, 10 Center Drive, MSC 1276, NIH Building 10 CRC 6-5340, Bethesda, MD, 20892-1276, USA.
Pediatrics & Developmental Neuroscience Branch, National Institute of Mental Health, Bethesda, MD, USA.
J Autism Dev Disord. 2018 Nov;48(11):3702-3710. doi: 10.1007/s10803-017-3180-7.
Little is known about suicidal ideation in youth with autism spectrum disorder (ASD), making it difficult to identify those at heightened risk. This study describes the prevalence of thoughts about death and suicide in 107 verbal youth with ASD with non-verbal IQ >55, assessed during inpatient psychiatric admission. Per parent report, 22% of youth with ASD had several day periods when they talked about death or suicide "often," or "very often." Clinical correlates included the presence of a comorbid mood (OR 2.71, 95% CI 1.12-6.55) or anxiety disorder (OR 2.32, 95% CI 1.10-4.93). The results suggest a need for developmentally appropriate suicide risk screening measures in ASD. Reliable detection of suicidal thoughts in this high-risk population will inform suicide prevention strategies.
关于自闭症谱系障碍(ASD)青少年的自杀意念知之甚少,因此很难识别那些处于高风险中的人。本研究描述了在住院精神病入院期间评估的 107 名具有非言语智商 >55 的言语 ASD 青少年中,对死亡和自杀的想法的流行程度。根据父母的报告,22%的 ASD 青少年有几天经常或非常频繁地谈论死亡或自杀。临床相关性包括共患心境障碍(OR 2.71,95%CI 1.12-6.55)或焦虑障碍(OR 2.32,95%CI 1.10-4.93)。结果表明,ASD 中需要制定适合发育阶段的自杀风险筛查措施。在这一高危人群中可靠地检测自杀意念将为自杀预防策略提供信息。