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测试简化检索策略对更新系统评价的有效性。

Testing the effectiveness of simplified search strategies for updating systematic reviews.

作者信息

Rice Maureen, Ali Muhammad Usman, Fitzpatrick-Lewis Donna, Kenny Meghan, Raina Parminder, Sherifali Diana

机构信息

McMaster Evidence Review and Synthesis Centre, McMaster University, 1280 Main St. W., McMaster Innovation Park, Room 207A, Hamilton, Ontario L8S 4K1, Canada; Department of Health Research Methods, Evidence and Impact, Faculty of Health Sciences, McMaster University, Hamilton, Ontario L8L 2X2, Canada.

McMaster Evidence Review and Synthesis Centre, McMaster University, 1280 Main St. W., McMaster Innovation Park, Room 207A, Hamilton, Ontario L8S 4K1, Canada; School of Nursing, Faculty of Health Sciences, McMaster University, Health Sciences Centre Room HSC-3N25F, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada.

出版信息

J Clin Epidemiol. 2017 Aug;88:148-153. doi: 10.1016/j.jclinepi.2017.06.005. Epub 2017 Jun 16.

Abstract

OBJECTIVE

The objective of the study was to test the overall effectiveness of a simplified search strategy (SSS) for updating systematic reviews.

STUDY DESIGN AND METHODS

We identified nine systematic reviews undertaken by our research group for which both comprehensive and SSS updates were performed. Three relevant performance measures were estimated, that is, sensitivity, precision, and number needed to read (NNR).

RESULTS

The update reference searches for all nine included systematic reviews identified a total of 55,099 citations that were screened resulting in final inclusion of 163 randomized controlled trials. As compared with reference search, the SSS resulted in 8,239 hits and had a median sensitivity of 83.3%, while precision and NNR were 4.5 times better. During analysis, we found that the SSS performed better for clinically focused topics, with a median sensitivity of 100% and precision and NNR 6 times better than for the reference searches. For broader topics, the sensitivity of the SSS was 80% while precision and NNR were 5.4 times better compared with reference search.

CONCLUSION

SSS performed well for clinically focused topics and, with a median sensitivity of 100%, could be a viable alternative to a conventional comprehensive search strategy for updating this type of systematic reviews particularly considering the budget constraints and the volume of new literature being published. For broader topics, 80% sensitivity is likely to be considered too low for a systematic review update in most cases, although it might be acceptable if updating a scoping or rapid review.

摘要

目的

本研究的目的是测试一种简化搜索策略(SSS)用于更新系统评价的总体有效性。

研究设计与方法

我们确定了研究小组进行的9项系统评价,针对这些评价进行了全面更新和SSS更新。估计了三项相关性能指标,即敏感性、精确性和阅读需要量(NNR)。

结果

所有9项纳入的系统评价的更新参考文献搜索共识别出55,099条待筛选的引文,最终纳入163项随机对照试验。与参考文献搜索相比,SSS产生了8,239条命中结果,中位敏感性为83.3%,而精确性和NNR则高出4.5倍。在分析过程中,我们发现SSS在临床重点主题方面表现更好,中位敏感性为100%,精确性和NNR比参考文献搜索高出6倍。对于更广泛的主题,SSS的敏感性为80%,而精确性和NNR与参考文献搜索相比高出5.4倍。

结论

SSS在临床重点主题方面表现良好,中位敏感性为100%,尤其考虑到预算限制和新发表文献的数量,对于更新这类系统评价而言,它可能是传统全面搜索策略的可行替代方案。对于更广泛的主题,在大多数情况下,80%的敏感性可能被认为对于系统评价更新过低,尽管如果是更新范围界定或快速评价可能是可接受的。

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