Song Shuang-Shuang, Wang Jian-Hong, Fu Wei-Wei, Li Ying, Sui Qing-Lan, Liu Xue-Jun
Department of Radiology, the Affiliated Hospital of Qingdao University, Qingdao, China.
Organ Transplantation Center, the Affiliated Hospital of Qingdao University, Qingdao, China.
World Neurosurg. 2017 Sep;105:1036.e1-1036.e3. doi: 10.1016/j.wneu.2017.06.058. Epub 2017 Jun 16.
We analyzed a case of medulloblastoma with atypical dynamic imaging changes retrospectively to summarize the atypical magnetic resonance imaging (MRI) features of medulloblastoma by reviewing the literature.
An atypical case of medulloblastoma in the cerebellar hemisphere confirmed by pathology was analyzed retrospectively, and the literature about it was reviewed.
The radiologic findings of the patient were based on 3 examinations. The first examination showed that the cortex of the bilateral cerebellar hemisphere had diffuse nodular thickening, with a high signal on diffusion-weighted imaging and significant enhancement. Contrast enhancement MRI 1 year later showed the signal of cerebellar hemisphere returned to normal but revealed an enhanced nodule. A reexamination 6 months later showed an irregular mass with a high-density shadow in the cerebellar vermis on CT scan. The T2-weighted image revealed multiple degenerative cysts, and the mass had significant enhancement.
The radiologic characteristics of atypical medulloblastomas vary in adults and children. Understanding the radiologic characteristics of medulloblastomas, such as MRI features, age of onset, and location of atypical medulloblastomas, can help improve the diagnosis of medulloblastomas.
通过回顾文献，对1例具有非典型动态影像学变化的髓母细胞瘤病例进行回顾性分析，总结髓母细胞瘤的非典型磁共振成像（MRI）特征。
回顾性分析1例经病理证实的小脑半球非典型髓母细胞瘤病例，并复习相关文献。
该患者的影像学表现基于3次检查。首次检查显示双侧小脑半球皮质弥漫性结节状增厚，在扩散加权成像上呈高信号且强化明显。1年后的对比增强MRI显示小脑半球信号恢复正常，但出现一个强化结节。6个月后的复查显示CT扫描小脑蚓部有一个不规则肿块及高密度影。T2加权像显示多个退行性囊肿，肿块强化明显。
非典型髓母细胞瘤的影像学特征在成人和儿童中有所不同。了解髓母细胞瘤的影像学特征，如MRI表现、发病年龄及非典型髓母细胞瘤的位置，有助于提高髓母细胞瘤的诊断水平。
