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计算机断层扫描在髓母细胞瘤治疗中的应用

Computed tomography in management of medulloblastomas.

作者信息

Sandhu A, Kendall B

机构信息

Hospital for Sick Children, London, England.

出版信息

Neuroradiology. 1987;29(5):444-52. doi: 10.1007/BF00341741.

DOI:10.1007/BF00341741
PMID:3683833
Abstract

The neuroradiological studies of 116 patients with histologically verified medulloblastomas, which had been examined with plain and contrast-enhanced computed tomography (CT), were reviewed. The typical CT appearances of a well-defined, hyperdense enhancing mass in the vermis, with surrounding oedema, occurred in 60% of this series. Atypical features include calcification (17%), cystic or necrotic regions (47%) or poorly defined margins and lack of enhancement (7%). Such features in a vermis mass presenting in the first decade, especially in a boy, should not be considered against the diagnosis of medulloblastoma, but may be misleading when the tumour predominantly involves a cerebellar hemisphere.

摘要

回顾了116例经组织学证实为髓母细胞瘤患者的神经放射学研究,这些患者均接受了平扫及增强计算机断层扫描(CT)检查。该系列病例中,60%表现为典型的CT征象,即蚓部有边界清晰、强化的高密度肿块,并伴有周围水肿。非典型特征包括钙化(17%)、囊性或坏死区域(47%),或边界不清及无强化(7%)。十岁前出现的蚓部肿块如有这些特征,尤其是在男孩中,不应排除髓母细胞瘤的诊断,但当肿瘤主要累及小脑半球时可能会产生误导。

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1
Computed tomography in management of medulloblastomas.计算机断层扫描在髓母细胞瘤治疗中的应用
Neuroradiology. 1987;29(5):444-52. doi: 10.1007/BF00341741.
2
Medulloblastoma with Atypical Dynamic Imaging Changes: Case Report with Literature Review.具有非典型动态成像变化的髓母细胞瘤:病例报告及文献综述
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[Adult cerebellar medulloblastoma: imaging findings in eight cases].[成人小脑髓母细胞瘤:8例影像学表现]
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Paediatric medulloblastoma: atypical CT features at presentation in the SIOP II trial.小儿髓母细胞瘤:SIOP II试验中初诊时的非典型CT特征
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Radiology. 1982 Jul;144(1):97-102. doi: 10.1148/radiology.144.1.6979760.
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Computerized tomographic findings in medulloblastomas.髓母细胞瘤的计算机断层扫描结果
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Neuroradiology. 2011 Jun;53(6):387-96. doi: 10.1007/s00234-010-0829-8. Epub 2011 Jan 29.
2
Primitive neuroectodermal tumors of the central nervous system.中枢神经系统原始神经外胚层肿瘤
Brain Pathol. 1997 Apr;7(2):765-84. doi: 10.1111/j.1750-3639.1997.tb01063.x.
3
Adult medulloblastoma: review of 13 cases with emphasis on MRI.
Neuroradiology. 1995 Feb;37(2):104-8. doi: 10.1007/BF00588622.

本文引用的文献

1
Computerized tomographic findings in medulloblastomas.髓母细胞瘤的计算机断层扫描结果
Comput Radiol. 1982 Mar-Apr;6(2):83-91. doi: 10.1016/0730-4862(82)90150-0.
2
Less common CT features of medulloblastoma.髓母细胞瘤不常见的CT特征。
Radiology. 1982 Jul;144(1):97-102. doi: 10.1148/radiology.144.1.6979760.
3
CT findings of medulloblastoma.髓母细胞瘤的CT表现。
4
MR imaging of a hemorrhagic medulloblastoma.出血性髓母细胞瘤的磁共振成像
Neuroradiology. 1989;31(4):371. doi: 10.1007/BF00344191.
5
Cystic medulloblastoma.
Neuroradiology. 1989;31(4):369-70. doi: 10.1007/BF00344190.
6
Paediatric medulloblastoma: atypical CT features at presentation in the SIOP II trial.小儿髓母细胞瘤:SIOP II试验中初诊时的非典型CT特征
Neuroradiology. 1991;33(2):140-2. doi: 10.1007/BF00588252.
Childs Brain. 1984;11(1):60-8. doi: 10.1159/000120160.
4
Midline posterior fossa neoplasms without lateral ventricular enlargement.无侧脑室扩大的后颅窝中线肿瘤
JAMA. 1971 Jan 4;215(1):89-93.
5
Computed tomography in the follow-up of medulloblastomas and ependymomas.髓母细胞瘤和室管膜瘤随访中的计算机断层扫描
Radiology. 1978 Jul;128(1):57-63. doi: 10.1148/128.1.57.
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Spectrum of medulloblastomas demonstrated by computed tomography.
Radiology. 1978 Jan;126(1):137-41. doi: 10.1148/126.1.137.
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The CT scanner in posterior fossa tumours of childhood.儿童后颅窝肿瘤的CT扫描仪
Br J Radiol. 1979 Oct;52(622):769-76. doi: 10.1259/0007-1285-52-622-769.
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Primary tumors and other masses of the cerebellum and fourth ventricle: differential diagnosis by computed tomography.小脑和第四脑室的原发性肿瘤及其他肿块:通过计算机断层扫描进行鉴别诊断
Neuroradiology. 1977 Dec 31;14(4):153-74. doi: 10.1007/BF00496979.