Su Yuehui, Zhang Mengzhen, Zhang Weiwei, Shi Huirong
Department of Gynecology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Pak J Pharm Sci. 2017 Jan;30(1 Suppl):329-334.
This paper aims to discuss the clinical significance of laparotomy nerve sparing radical hysterectomy (NSRH) on rectal function of early cervical cancer patients, compared with conventional radical hysterectomy. 30 cases of early cervical carcinoma patients who had received surgery in the First Affiliated Hospital of Zhengzhou University from June 2010 to June 2014 were selected as subjects. Patients were divided into two groups, with 15 in each gorup, in which Group A had received NSRH, B received CRH, and all them were in stage IB-IIA1. In the surgery, 2 cases of patients in NSRH group failed in nerve sparing operation, and were grouped into CRH group. The postoperative condition of two groups were observed, recorded and compared as well, especially the comparison between the postoperative recovery condition of rectal function of two groups. The comparison were conducted between two groups on the operation time, bleeding volume, quantity of cleaned pelvic lymph node, resection length of parametrium, resection length of vagina, etc. There was no statistical significance (P>0.05). The postoperative urinary catheter indwelling time in NSRH group was shorter than CRH group, with statistical significance (P<0.05). The postoperative maximum urine flow, maximum cystometric capacity, maximum detrusor pressure and urinary complications in NSRH group were significantly better than the postoperative condition in CRH group, with statistical significance (P<0.05). NSRH surgery was safe and reliable, which not only had obvious advantage in improving postoperative rectal function and bladder function, but also had a significantly effect on improving postoperative life quality as well. The results proved that patients had low disease morbidity and with great clinical significance.
本文旨在探讨腹式保留神经广泛性子宫切除术(NSRH)与传统广泛性子宫切除术相比,对早期宫颈癌患者直肠功能的临床意义。选取2010年6月至2014年6月在郑州大学第一附属医院接受手术的30例早期宫颈癌患者作为研究对象。将患者分为两组,每组15例,其中A组接受NSRH手术,B组接受传统广泛性子宫切除术(CRH),所有患者均处于IB-IIA1期。手术中,NSRH组有2例患者保留神经手术失败,归入CRH组。观察、记录并比较两组患者术后情况,尤其是两组直肠功能的术后恢复情况比较。比较两组患者的手术时间、出血量、盆腔淋巴结清扫数量、宫旁组织切除长度、阴道切除长度等。差异无统计学意义(P>0.05)。NSRH组术后留置尿管时间短于CRH组,差异有统计学意义(P<0.05)。NSRH组术后最大尿流率、最大膀胱容量、最大逼尿肌压力及泌尿系统并发症情况均明显优于CRH组,差异有统计学意义(P<0.05)。NSRH手术安全可靠,不仅在改善术后直肠功能和膀胱功能方面具有明显优势,而且对提高术后生活质量也有显著作用。结果证明该手术患者疾病发生率低,具有重要临床意义。