Yuan Lingzhi, Tang Dan, Peng Jin, Qu Nanfang, Yue Chun, Wang Fen
Department of Gastroenterology, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2017 May 28;42(5):558-564. doi: 10.11817/j.issn.1672-7347.2017.05.013.
To investigate the correlation between certain unhealthy lifestyles and the incidence of gastroesophageal reflux disease (GERD), thus to provide the lifestyle guidelines for GERD patients. Methods: Retrospective study were conducted for 402 GERD and 276 non-GERD out-patients in Department of Gastroenterology, Third Xiangya Hospital, Central South University from August, 2014 to August, 2015 based on questionnaire survey, then the correlation of unhealthy lifestyles with GERD were analyzed. Results: The top 10 common symptoms for GERD were as follows: reflux, acid regurgitation, postprandial fullness, heartburn, swallow obstruction or pain, epigastric burning sensation, paraesthesia pharynges, poststernal pain, chronic laryngopharyngitis, and chronic cough. The top 8 unhealthy habits closely related to GERD were as follows: fast-eating, over-eating, spicy preferred diet, sweets preferred diet, anxious, soup preferred diet, high-fat diet, and hot eating. Single-factor analysis showed that GERD was markedly correlated to gender (male), age (≥60 years), BMI, smoking, alcohol, fast-eating, over-eating, hot-eating, spicy preferred diet, high-fat diet, acid preferred diet, sweets preferred diet, hard food preference, strong tea preference, coffee preference, immediately on bed after meal, difficult defecation, dyscoimesis, anxious, and too tight belt, respectively (P<0.05). Logistic multiple regression analysis indicated that the largest risk factor for GERD was the fast-eating (OR=3.214, 95% CI 2.171 to 4.759, P<0.001) followed by the over-eating (OR=2.936, 95% CI 1.981 to 4.350, P<0.001), elderly population (OR=2.047, 95% CI 1.291 to 3.244, P=0.002), too tight belt (OR=2.003, 95% CI 1.013 to 3.961, P=0.046), and hot-eating (OR=1.570, 95% CI 1.044 to 2.362, P=0.030). Conclusion: The elderly people are at high risk for GERD, and unhealthy habits like fast-eating, over-eating, too tight belt, and hot-eating is closely related to GERD. The lifestyles such as chewing food thoroughly, splitting the meals up, warm and cool diet, keeping patients out of the too tight belt are necessary for GERD patients.
探讨某些不健康生活方式与胃食管反流病(GERD)发病率之间的相关性,从而为GERD患者提供生活方式指导。方法:2014年8月至2015年8月,对中南大学湘雅三医院消化内科402例GERD门诊患者和276例非GERD门诊患者进行回顾性研究,通过问卷调查分析不健康生活方式与GERD的相关性。结果:GERD最常见的10种症状依次为:反流、反酸、餐后饱胀、烧心、吞咽梗阻或疼痛、上腹部烧灼感、咽部异物感、胸骨后疼痛、慢性咽喉炎、慢性咳嗽。与GERD密切相关的8种不健康习惯依次为:进食快、暴饮暴食、喜食辛辣、喜食甜食、焦虑、喜食汤类、高脂饮食、烫食。单因素分析显示,GERD与性别(男性)、年龄(≥60岁)、BMI、吸烟、饮酒、进食快、暴饮暴食、烫食、喜食辛辣、高脂饮食、喜食酸性食物、喜食甜食、喜食硬质食物、喜饮浓茶、喜饮咖啡、餐后立即卧床、排便困难、排便不规律、焦虑、腰带过紧分别显著相关(P<0.05)。Logistic多因素回归分析表明,GERD最大的危险因素是进食快(OR=3.214,95%CI 2.171至4.759,P<0.001),其次是暴饮暴食(OR=2.936,95%CI 1.981至4.350,P<0.001)、老年人群(OR=2.047,95%CI 1.291至3.244,P=0.002)、腰带过紧(OR=2.003,95%CI 1.013至3.961,P=0.046)和烫食(OR=1.570,95%CI 1.044至2.362,P=0.030)。结论:老年人GERD发病风险高,进食快、暴饮暴食、腰带过紧、烫食等不健康习惯与GERD密切相关。GERD患者应养成细嚼慢咽、少食多餐、饮食温凉、避免腰带过紧等生活方式。