Lipshitz J, Klose C W
Obstet Gynecol. 1985 Sep;66(3 Suppl):16S-18S.
The use of oxytocin in labor has the inherent danger of producing uterine hyperstimulation with resultant fetal distress. When produced by gradual titration of intravenous oxytocin, discontinuation of the medication is usually sufficient to reverse the process. However, the rapid administration of a large intravenous dose of oxytocin, as occurred in this patient, may result in hypertonic uterine contractions and fetal distress unresponsive to traditional measures. The rationale for using a tocolytic drug to reverse the uterine hypertonus, produce intrauterine fetal resuscitation, and prevent cesarean section is discussed in this report.
分娩时使用缩宫素存在引发子宫过度刺激并导致胎儿窘迫的固有风险。通过静脉滴注缩宫素逐渐增加剂量引发这种情况时，通常停止用药就足以逆转这一过程。然而，像该患者这样快速静脉推注大剂量缩宫素，可能会导致子宫强直性收缩以及胎儿窘迫，而传统措施对此并无效果。本报告讨论了使用宫缩抑制剂来逆转子宫张力亢进、进行宫内胎儿复苏并避免剖宫产的理论依据。
