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应激性溃疡的预防与处理

Prophylaxis and management of stress ulcers.

作者信息

Anderberg B, Sjödahl R

出版信息

Scand J Gastroenterol Suppl. 1985;110:101-4. doi: 10.3109/00365528509095839.

DOI:10.3109/00365528509095839
PMID:2862695
Abstract

Stress ulcers are located in the body and fundic part of the stomach. They occur in the majority of severely ill or injured patients, but only about 10% will bleed. The most effective prophylaxis are measures against the condition giving rise to risk factors as septicaemia, shock and malnutrition. The medical prophylaxis consists of antacids and/or histamine2-blockers. Most bleedings will stop after intensive care and medication with vasopressin particularly if risk factors can be eliminated. Gastric surgery should be the last step in the treatment of bleeding stress ulcers and then we recommend non-resectional surgery as gastric devascularisation or suture ligation of bleeding vessels.

摘要

应激性溃疡位于胃体和胃底部。大多数重症或受伤患者都会出现应激性溃疡,但只有约10%的患者会出血。最有效的预防措施是针对引发危险因素(如败血症、休克和营养不良)的情况采取措施。药物预防包括使用抗酸剂和/或组胺2受体阻滞剂。经过重症监护和使用血管加压素治疗后,大多数出血会停止,特别是如果能够消除危险因素。胃手术应是应激性溃疡出血治疗的最后一步,我们建议采用非切除性手术,如胃去血管化或出血血管缝扎术。

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1
Prophylaxis and management of stress ulcers.应激性溃疡的预防与处理
Scand J Gastroenterol Suppl. 1985;110:101-4. doi: 10.3109/00365528509095839.
2
Stress ulcer prophylaxis: still a valid option in the 1990s?应激性溃疡的预防:在20世纪90年代仍是一种有效的选择吗?
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Prophylaxis of stress ulcers: antacid titration vs. histamine2-receptor blockade.应激性溃疡的预防:抗酸剂滴定法与组胺2受体阻滞剂对比
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[Stress ulcerations: pathogenesis and prevention].[应激性溃疡:发病机制与预防]
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引用本文的文献

1
Appropriateness and Associated Factors of Stress Ulcer Prophylaxis for Surgical Inpatients of Orthopedics Department in a Tertiary Hospital: A Cross-Sectional Study.某三级医院骨科手术患者应激性溃疡预防的合理性及相关因素:一项横断面研究
Front Pharmacol. 2022 Jun 2;13:881063. doi: 10.3389/fphar.2022.881063. eCollection 2022.
2
Stress ulcer prophylaxis guidelines: Are they being implemented in Lebanese health care centers?应激性溃疡预防指南:它们在黎巴嫩医疗保健中心得到实施了吗?
World J Gastrointest Pharmacol Ther. 2011 Aug 6;2(4):27-35. doi: 10.4292/wjgpt.v2.i4.27.