Üstyol A, Kökali F, Duru N, Duman M A, Elevli M
Department of Pediatrics Istanbul, Haseki Training and Research Hospital, Istanbul, Turkey.
J Clin Pharm Ther. 2017 Dec;42(6):780-782. doi: 10.1111/jcpt.12573. Epub 2017 Jun 18.
Cases of Cushing's syndrome (CS) following ocular steroid use have been reported in recent years, albeit rarely.
We report a case of iatrogenic CS in a child induced by fluorometholone-containing eyedrops. Our patient was referred to our endocrinology clinic due to rapid weight gain. His history revealed that 1.5 months previously he had been started on fluorometholone eyedrops.
To the best of our knowledge, no cases of CS have been reported following ocular fluorometholone use. Although eyedrops containing potent glucocorticoids may lead to CS, fluorometholone, a relatively less potent steroid, may also cause the syndrome, as in our case.
近年来虽有使用眼部类固醇后发生库欣综合征（CS）的病例报道，但极为罕见。
我们报告一例因含氟米龙滴眼液导致医源性CS的儿童病例。我们的患者因体重迅速增加被转诊至我们的内分泌门诊。其病史显示，1.5个月前他开始使用氟米龙滴眼液。
据我们所知，此前尚无使用眼部氟米龙后发生CS的病例报道。尽管含强效糖皮质激素的滴眼液可能导致CS，但如我们病例所示，相对效力较弱的类固醇氟米龙也可能引发该综合征。
