Kolar Firdose R, Gogi Chaya L, Khudavand Mairunisabegum M, Choudhari Meera S, Patil Sindhu B
a Department of Botany , Akkamahadevi Women's University , Vijayapur , India.
Nat Prod Res. 2018 Jun;32(11):1324-1328. doi: 10.1080/14786419.2017.1342085. Epub 2017 Jun 18.
In this study, the antioxidant activity of aqueous and ethanol extracts of four plants from the genus Cassia were evaluated by various antioxidant assays, including ferric reducing antioxidant power (FRAP), DPPH free radical scavenging, metal chelating activity, phosphomolybdenum reducing power, hydrogen peroxide radical scavenging, hydroxyl radical scavenging, deoxyribose degradation and β-carotene bleaching assay. The various antioxidant activities were compared to standard antioxidant such as ascorbic acid. All the extracts showed antioxidant activity in the tested methods. Among the four species, Cassia auriculata has been found to possess highest activity in most of the tested models. In addition to the antioxidant activity, the total phenolics and flavonoids were measured in the extracts. The ethanolic extract exhibited highest phenolics and flavonoid contents and had also shown potent antioxidant activity in comparison to the aqueous extracts. The possible antioxidant mechanism of the ethanol extract can be due to its hydrogen or electron donating and direct free radical scavenging properties. Hence, the ethanol extract represents a source of potential antioxidants that could be used in pharmaceutical industries.
在本研究中，通过多种抗氧化测定法，包括铁还原抗氧化能力（FRAP）、DPPH自由基清除、金属螯合活性、磷钼酸还原能力、过氧化氢自由基清除、羟基自由基清除、脱氧核糖降解和β-胡萝卜素漂白测定，评估了决明属四种植物的水提取物和乙醇提取物的抗氧化活性。将各种抗氧化活性与标准抗氧化剂如抗坏血酸进行比较。所有提取物在测试方法中均表现出抗氧化活性。在这四个物种中，已发现耳叶决明在大多数测试模型中具有最高活性。除了抗氧化活性外，还测定了提取物中的总酚和黄酮类化合物。乙醇提取物表现出最高的酚类和黄酮类含量，并且与水提取物相比也表现出较强的抗氧化活性。乙醇提取物可能的抗氧化机制可能归因于其供氢或供电子以及直接清除自由基的特性。因此，乙醇提取物代表了一种可用于制药行业的潜在抗氧化剂来源。
