Buravlev V M
Zh Nevropatol Psikhiatr Im S S Korsakova. 1978;78(7):1070-5.
The author studied the influence on the adaptation of the nervous tissue explantations from 25 fetuses of schizophrenic mothers and a similar amount of fetuses from normal women (embryonal development--7-12 weeks) during the initial period of explantation in vitro (5-6 days) with 10 psychopharmacological preparations (aminasine, majeptile, stelasine, triphtasine, tesercin, theralen, haloperidol, eglonyl, mellipramin, seduxen). Their final concentration in a nourishing medium was approximately the same as in the blood of schizophrenic patients, treated by phenothiasine preparations. The adaptation of the fetus pervous tissue from schizophrenic mothers differed from the corresponding reaction of fetus brain explantation from normal women. There was a tendency to a higher stability of experimental cultures. However, there were differences depending upon the character of introduced drugs.
作者研究了10种精神药理学制剂（氨基丙嗪、吗茚酮、氯氮卓、曲他嗪、替色林、泰尔登、氟哌啶醇、乙磺半胱氨酸、丙咪嗪、安定）对来自25名精神分裂症母亲的胎儿以及相同数量正常女性胎儿（胚胎发育7 - 12周）的神经组织外植体在体外培养初期（5 - 6天）适应性的影响。它们在营养培养基中的最终浓度与接受吩噻嗪类制剂治疗的精神分裂症患者血液中的浓度大致相同。来自精神分裂症母亲的胎儿神经组织的适应性与正常女性胎儿脑外植体的相应反应不同。实验培养物有更高稳定性的趋势。然而，根据所引入药物的性质存在差异。
