Kumar Arun, Sundaram Sandhya, Rayala Suresh K, Venkatraman Ganesh
a Department of Biotechnology , Indian Institute of Technology Madras (IITM) , Chennai , India.
b Departments of Pathology , Sri Ramachandra University , Porur, Chennai , India.
Small GTPases. 2019 Jul;10(4):264-270. doi: 10.1080/21541248.2017.1322667. Epub 2017 Jun 23.
Post translational modifications of RUNX3 have been shown to play an important role in directing RUNX3 functions. In this review we highlight the phosphorylation dependent functions of RUNX3 as regulated by PAK1 and its implications on tumorigenesis.
RUNX3的翻译后修饰已被证明在指导RUNX3功能方面发挥重要作用。在本综述中，我们重点介绍了由PAK1调节的RUNX3的磷酸化依赖性功能及其对肿瘤发生的影响。
