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剖腹探查术和术中内镜检查在胶囊内镜和深内镜检查时代前后对不明原因胃肠道出血的作用:一家三级中心的经验。

Laparotomy and intraoperative enteroscopy for obscure gastrointestinal bleeding before and after the era of video capsule endoscopy and deep enteroscopy: A tertiary center experience.

机构信息

Department of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha, NE, United States; CURE Digestive Diseases Research Center (DDRC) - GI Hemostasis Unit, Los Angeles, CA, United States.

CURE Digestive Diseases Research Center (DDRC) - GI Hemostasis Unit, Los Angeles, CA, United States; David Geffen School of Medicine at UCLA, Los Angeles, CA, United States; VA Greater Los Angeles Healthcare System, Los Angeles, CA, United States.

出版信息

Am J Surg. 2018 Apr;215(4):603-609. doi: 10.1016/j.amjsurg.2017.05.018. Epub 2017 Jun 19.

Abstract

BACKGROUND

To evaluate roles of intraoperative endoscopy (IOE) in management of severe obscure GI bleeding (OGIB) before vs. after introduction of video capsule endoscopy (VCE) and deep enteroscopy (DE).

METHODS

We retrospectively reviewed prospectively collected data of patients undergoing IOE for severe OGIB in a tertiary referral center.

RESULTS

52 patients had laparotomy/IOE for OGIB, 11 pre and 41 post VCE/DE eras. In the pre VCE/DE era, 36.4% (4/11) had preoperative presumptive diagnoses while in the post VCE/DE era presumptive diagnoses were made in 48.8% (20/41) (p = 0.18). Preoperative evaluation led to correct diagnoses in 18.2% (2/11) in the pre and 51.2% (21/41) in the post VCE/DE era (p = 0.09). Vascular lesions and ulcers were the most common diagnoses, but rebleeding was common. No rebleeding was found among patients with tumors, Meckel's diverticulum, and aortoenteric fistula.

CONCLUSIONS

Presumptive diagnoses in the post VCE/DE era were usually accurate. If VCE or DE are negative, the probability of negative IOE is high. Patients with tumors and Meckel's diverticulum were the best candidates for IOE.

摘要

背景

评估术中内镜(IOE)在视频胶囊内镜(VCE)和深部内镜(DE)引入前后对严重不明原因胃肠道出血(OGIB)的治疗作用。

方法

我们回顾性分析了在一家三级转诊中心因严重 OGIB 而行 IOE 的患者的前瞻性收集数据。

结果

52 例患者因 OGIB 行剖腹手术/IOE,11 例在 VCE/DE 前,41 例在 VCE/DE 后。在 VCE/DE 前,36.4%(4/11)有术前推测诊断,而在 VCE/DE 后,推测诊断为 48.8%(20/41)(p=0.18)。术前评估在 VCE/DE 前正确诊断率为 18.2%(2/11),而在 VCE/DE 后为 51.2%(21/41)(p=0.09)。血管病变和溃疡是最常见的诊断,但再出血很常见。在肿瘤、 Meckel 憩室和主动脉肠瘘患者中未发现再出血。

结论

VCE/DE 后的推测诊断通常较为准确。如果 VCE 或 DE 为阴性,则 IOE 为阴性的可能性较高。肿瘤和 Meckel 憩室患者是 IOE 的最佳候选者。

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