Van de Bruaene Cedric, Hindryckx Pieter, Van de Bruaene Laurens, De Looze Danny
Department of Gastroenterology, Ghent University Hospital, De Pintelaan 185, 1K12, 9000, Ghent, Belgium.
Department of Internal Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.
Curr Gastroenterol Rep. 2018 Mar 7;20(2):5. doi: 10.1007/s11894-018-0610-4.
Gastrointestinal bleeding originating from the small bowel (SB) poses a challenge to the treating gastroenterologist. Once diagnosed, management is not a walk in the park either. This review intends to summarize the current state-of-the-art evidence in a complete way with special attention for vascular and ulcerative lesions, to provide the reader with a clinical guide and flow chart towards SB bleeding.
Absence of SB bleeding lesions on CE does not directly yield better prognosis; although having a lower rebleeding rate the first 2 years, rebleeding in the long term is high. Push enteroscopy can play an early role in patients with SB bleeding if suspicion of angioectasia is high, since these lesions tend to be located in the proximal SB. Endoscopic management of angioectasia is, however, difficult and shows poor results. Capsule endoscopy (CE) or device-assisted enteroscopy (DAE) remain the diagnostic mainstay in SB bleeding, choosing one over the other based upon patient characteristics and expected lesions.
源于小肠(SB)的胃肠道出血给治疗的胃肠病学家带来了挑战。一旦确诊,治疗也并非易事。本综述旨在全面总结当前的最新证据,特别关注血管性和溃疡性病变,为读者提供针对小肠出血的临床指南和流程图。
小肠胶囊内镜(CE)检查未发现小肠出血病变并不直接意味着预后更好;虽然在最初2年再出血率较低,但长期再出血率较高。如果高度怀疑血管扩张,推进式小肠镜检查可在小肠出血患者中早期发挥作用,因为这些病变往往位于近端小肠。然而,血管扩张的内镜治疗困难且效果不佳。小肠胶囊内镜(CE)或器械辅助小肠镜检查(DAE)仍然是小肠出血的主要诊断方法,应根据患者特征和预期病变选择其中一种。