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雌激素对肌腱和韧带代谢及功能的影响。

The effect of estrogen on tendon and ligament metabolism and function.

作者信息

Leblanc D R, Schneider M, Angele P, Vollmer G, Docheva D

机构信息

Experimental Surgery and Regenerative Medicine, Department of Surgery, Ludwig-Maximilians-University Munich, Germany.

Experimental Trauma Surgery, Department of Trauma Surgery, University Regensburg Medical Centre, Regensburg, Germany.

出版信息

J Steroid Biochem Mol Biol. 2017 Sep;172:106-116. doi: 10.1016/j.jsbmb.2017.06.008. Epub 2017 Jun 16.

DOI:10.1016/j.jsbmb.2017.06.008
PMID:28629994
Abstract

Tendons and ligaments are crucial structures inside the musculoskeletal system. Still many issues in the treatment of tendon diseases and injuries have yet not been resolved sufficiently. In particular, the role of estrogen-like compound (ELC) in tendon biology has received until now little attention in modern research, despite ELC being a well-studied and important factor in the physiology of other parts of the musculoskeletal system. In this review we attempt to summarize the available information on this topic and to determine many open questions in this field.

摘要

肌腱和韧带是肌肉骨骼系统内的关键结构。然而,肌腱疾病和损伤的治疗中仍有许多问题尚未得到充分解决。特别是,雌激素样化合物(ELC)在肌腱生物学中的作用,尽管在肌肉骨骼系统其他部位的生理学中是一个经过充分研究且重要的因素,但在现代研究中至今很少受到关注。在这篇综述中,我们试图总结关于这个主题的现有信息,并确定该领域中许多尚未解决的问题。

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