Şuşan Monica, Cristea Andreea Maria, Drăghici George Andrei, Nica Dragoş Vasile, Florescu Sorin, Damian Cosmin Grațian
Department of Internal Medicine, Centre for Preventive Medicine, Eftimie Murgu Square No. 2, 300041 Timișoara, Romania.
Research Center for Pharmaco-Toxicological Evaluations, Faculty of Pharmacy, "Victor Babes" University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 300041 Timisoara, Romania.
Medicina (Kaunas). 2025 Apr 1;61(4):643. doi: 10.3390/medicina61040643.
: Knee joint injuries incur substantial healthcare and socioeconomic burdens worldwide. The connection between various demographic and clinical factors and meniscal injury patterns in patients undergoing surgery for meniscal rupture remains underexplored, especially in Eastern European cohorts. This study aimed to determine the influence of age, sex, and history of previous meniscal rupture on the patterns and types of knee joint injuries in adults aged 35 years and older undergoing surgery. A single-site exploratory retrospective analysis was conducted on 420 Romanian patients. The age of 35 years was selected as a cut-off for recruiting patients, as it marks the typical age at which early degenerative changes in the musculoskeletal system begin to emerge. Nonparametric/frequency analysis was applied to datasets stratified based on injury type-medial meniscal damage (MMD), lateral meniscal damage (LMD), and any patellar damage (APD). Logistic regression was used to determine influential predictors, including age, sex, and history of meniscal rupture. : Surgery was performed at a significantly younger age in patients with previous meniscus rupture ( < 0.001), but at a significantly older age in patients with co-occurring patellar lesions ( = 0.048). Men tended to be younger at the time of first surgery or any reoperations ( = 0.054) and displayed LMD significantly more often than MMD ( = 0.023). Significant differences existed in the distribution of different tear types in LMD ( < 0.001) and MMD ( < 0.001), with bucket handle tears and parrot beak tears being the most common. Male sex was associated with significantly higher odds of LMD ( = 0.046). Patients with previous meniscal rupture had a significantly and approximately threefold higher likelihood of presenting with MMD ( = 0.003). : Age, sex, and history of meniscal rupture significantly influence the patterns and prevalence of knee injuries in adults aged 35 years and older. These findings reveal a dynamic interplay between demographic factors and knee joint pathologies, providing a foundation for targeted prevention and treatment strategies. Future studies should expand to larger, diverse populations to refine these insights.
膝关节损伤在全球范围内造成了巨大的医疗和社会经济负担。在接受半月板破裂手术的患者中，各种人口统计学和临床因素与半月板损伤模式之间的联系仍未得到充分研究，尤其是在东欧人群中。本研究旨在确定年龄、性别和既往半月板破裂史对35岁及以上接受手术的成年人膝关节损伤模式和类型的影响。对420名罗马尼亚患者进行了单中心探索性回顾性分析。选择35岁作为招募患者的年龄界限，因为这标志着肌肉骨骼系统早期退行性变化开始出现的典型年龄。对基于损伤类型分层的数据集应用非参数/频率分析，损伤类型包括内侧半月板损伤（MMD）、外侧半月板损伤（LMD）和任何髌骨损伤（APD）。使用逻辑回归来确定有影响的预测因素，包括年龄、性别和半月板破裂史。：既往有半月板破裂的患者手术年龄明显更小（<0.001），但合并髌骨病变的患者手术年龄明显更大（=0.048）。男性首次手术或任何再次手术时往往更年轻（=0.054），并且LMD的发生率明显高于MMD（=0.023）。LMD（<0.001）和MMD（<0.001）中不同撕裂类型的分布存在显著差异，桶柄状撕裂和鹦鹉嘴状撕裂最为常见。男性性别与LMD的显著更高几率相关（=0.046）。既往有半月板破裂的患者出现MMD的可能性显著高出约三倍（=0.003）。：年龄、性别和半月板破裂史显著影响35岁及以上成年人膝关节损伤的模式和患病率。这些发现揭示了人口统计学因素与膝关节病理之间的动态相互作用，为有针对性的预防和治疗策略提供了基础。未来的研究应扩展到更大、更多样化的人群，以完善这些见解。
