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免疫功能正常患者的多病原性坏死性会厌炎

Multipathogenic necrotising supraglottitis in an immunocompetent patient.

作者信息

Ahmed Jacob Joseph, Constable James Douglas, Kamani Tawakir, De Mriganka

机构信息

Otorhinolaryngology, Head and Neck Surgery, Royal Derby Hospital, Derby, UK.

出版信息

BMJ Case Rep. 2017 Jun 18;2017:bcr-2017-219631. doi: 10.1136/bcr-2017-219631.

DOI:10.1136/bcr-2017-219631
PMID:28630241
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5534817/
Abstract

Supraglottitis is a potentially life-threatening condition. It is now uncommon due to the type B vaccination and is more recently caused by , , non-type B, , and Very rarely, it can cause necrotising supraglottitis/epiglottitis, and this has been reported in immunocompromised individuals. We present a unique case of multipathogenic supraglottitis causing laryngeal fibrinoid necrosis in an immunocompetent patient. During his admission, the patient was critically unwell and required surgical intervention and tracheostomy. However, he made a full recovery with no persisting morbidity. We believe that this was owed to the aggressive antimicrobial therapy, timely surgical management of the disease process and the patient’s immunocompetency.

摘要

会厌炎是一种可能危及生命的疾病。由于B型疫苗接种,现在这种疾病并不常见,最近它由非B型的[具体病菌1]、[具体病菌2]、[具体病菌3]以及[具体病菌4]引起。非常罕见的情况下,它会导致坏死性会厌炎/会厌炎,免疫功能低下的个体中曾有过相关报道。我们报告了一例独特的多病原性会厌炎病例,该病例在一名免疫功能正常的患者中导致了喉部纤维蛋白样坏死。在患者住院期间,病情危急,需要手术干预和气管切开术。然而,他完全康复,没有留下持续的病症。我们认为这归功于积极的抗菌治疗、对疾病进程的及时手术处理以及患者的免疫功能正常。

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本文引用的文献

1
A Case of Necrotizing Epiglottitis Due to Nontoxigenic Corynebacterium diphtheriae.一例由无毒力白喉棒状杆菌引起的坏死性会厌炎病例。
Pediatrics. 2015 Jul;136(1):e242-5. doi: 10.1542/peds.2014-3157. Epub 2015 Jun 8.
2
A rare case of necrotising epiglottitis.一例罕见的坏死性会厌炎病例。
J Surg Case Rep. 2011 Feb 1;2011(2):5. doi: 10.1093/jscr/2011.2.5.
3
Changing patterns in pediatric supraglottitis: a multi-institutional review, 1980 to 1992.
Laryngoscope. 1994 Nov;104(11 Pt 1):1314-22.