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一例来自地方病流行区的疑似结核性葡萄膜炎伴闭塞性血管炎病例。

A Case of Presumed Tuberculosis Uveitis with Occlusive Vasculitis from an Endemic Region.

作者信息

Başarır Berna, Karaküçük Yalçın, Altan Çiğdem, Şatana Banu, Ocak Bulut, İnal Aslı

机构信息

Beyoğlu Eye Training and Research Hospital, Ophthalmology Clinic, İstanbul, Turkey.

出版信息

Turk J Ophthalmol. 2017 Jun;47(3):169-173. doi: 10.4274/tjo.32548. Epub 2017 Jun 1.

Abstract

In this report, we present a case with presumed unilateral tuberculosis uveitis from an endemic region. A 23-year-old male presented with decreased vision in his left eye for 15 days. Visual acuities were 1.0 in his right eye and 0.3 in his left eye. Ophthalmologic examination was normal for the right eye. Slit-lamp examination revealed 2+ cells in the vitreous without anterior chamber reaction in his left eye. Fundus examination revealed occlusive vasculitis and granuloma. His history revealed that he had a respiratory infection with fever 3 months ago while visiting his native country, Rwanda, and was treated with non-specific antibiotic therapy. His visual symptom started 2 weeks after his systemic symptoms resolved. Laboratory findings included 15 mm induration in purified protein derivative tuberculin skin test, HIV negativity, and parenchymal lesions in chest X-ray. Bronchoalveolar lavage was negative for acid-fast bacillus. A pulmonary disease consultant reported presumed tuberculosis because of the patient's history. Anti-tuberculosis treatment was initiated. The patient's visual acuity improved rapidly and his signs regressed. A careful history should be taken from patients with uveitis. Travel to tuberculosis-endemic areas may be important for diagnosis and should be asked about directly.

摘要

在本报告中,我们呈现了一例来自地方病流行区的疑似单侧结核性葡萄膜炎病例。一名23岁男性因左眼视力下降15天就诊。右眼视力为1.0,左眼视力为0.3。右眼眼科检查正常。裂隙灯检查发现左眼玻璃体内有2+细胞,无前房反应。眼底检查发现闭塞性血管炎和肉芽肿。他的病史显示,3个月前他在访问祖国卢旺达时出现了伴有发热的呼吸道感染,并接受了非特异性抗生素治疗。他的视觉症状在全身症状缓解后2周开始出现。实验室检查结果包括结核菌素皮肤试验硬结直径为15mm、HIV阴性以及胸部X线检查发现实质性病变。支气管肺泡灌洗未发现抗酸杆菌。由于患者的病史,肺部疾病顾问报告疑似结核病。开始进行抗结核治疗。患者视力迅速改善,体征消退。对于葡萄膜炎患者应仔细询问病史。前往结核病流行地区的情况对于诊断可能很重要,应直接询问。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50f4/5468532/f2bb0853e748/TJO-47-169-g1.jpg

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