Vijayan Sarath, Xiong Zhenyu, Rudin Stephen, Bednarek Daniel R
University at Buffalo, Department of Physiology and Biophysics, Buffalo, New York, United States.
Toshiba Stroke and Vascular Research Center, Buffalo, New York, United States.
J Med Imaging (Bellingham). 2017 Jul;4(3):031203. doi: 10.1117/1.JMI.4.3.031203. Epub 2017 Jun 14.
Radiation backscattered from the patient can contribute substantially to skin dose in fluoroscopically guided interventions (FGIs). The distribution of backscatter is not spatially uniform, and use of a single backscatter factor cannot provide an accurate determination of skin dose. This study evaluates a method to determine the backscatter spatial distribution through convolution of a backscatter-to-primary (BP) point spread function (PSFn). The PSFn is derived for a pencil beam using EGSnrc Monte Carlo software and is convolved with primary distributions using a dose-tracking system. The backscatter distribution calculated using the convolution method is validated with Monte Carlo-derived distributions for three different size "uniform" fields and with XR-QA2 Gafchromic film for nonuniform x-ray fields obtained using region-of-interest (ROI) attenuators and compensation filters, both with homogenous poly-methyl methacrylate and nonhomogenous head phantoms. The BP ratios inside uniform fields were calculated within [Formula: see text] of that determined using EGSnrc. For shaped fields, the BP ratio in the unattenuated ROI was calculated within [Formula: see text] of that measured with film; in the beam-attenuated periphery, agreement was within [Formula: see text], due to the larger uncertainty of the dose-response curve of the film in the low-dose region. This backscatter PSFn convolution method is much faster than performing full-field Monte Carlo calculations and provides improved accuracy in skin dose distribution determination for FGI procedures.
在荧光透视引导介入操作(FGIs)中,从患者身上反向散射的辐射会对皮肤剂量产生显著影响。反向散射的分布在空间上并不均匀,使用单一的反向散射因子无法准确确定皮肤剂量。本研究评估了一种通过反向散射与原发射线(BP)点扩散函数(PSFn)卷积来确定反向散射空间分布的方法。使用EGSnrc蒙特卡罗软件为笔形束推导PSFn,并使用剂量跟踪系统将其与原发射线分布进行卷积。使用卷积方法计算得到的反向散射分布,通过三种不同尺寸“均匀”射野的蒙特卡罗推导分布,以及使用感兴趣区域(ROI)衰减器和补偿滤波器获得的非均匀X射线射野的XR-QA2变色膜进行验证,射野分别使用均匀聚甲基丙烯酸甲酯和非均匀头部模型。均匀射野内的BP比值计算结果与使用EGSnrc确定的值在[公式:见原文]范围内。对于成形射野,未衰减ROI内的BP比值计算结果与膜测量值在[公式:见原文]范围内;在射野衰减周边,由于低剂量区域膜剂量响应曲线的不确定性较大,一致性在[公式:见原文]范围内。这种反向散射PSFn卷积方法比进行全场蒙特卡罗计算快得多,并且在FGI程序的皮肤剂量分布确定中提供了更高的准确性。