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定量风险评估以指导剖宫产瘢痕妊娠的治疗。

Quantitative risk assessment to guide the treatment of cesarean scar pregnancy.

作者信息

Fang Qingxian, Sun Li, Tang Yunhui, Qian Cuifeng, Yao Xiaoying

机构信息

Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.

Department of Obstetrics and Gynecology of Shanghai Medical College, Fudan University, Shanghai, China.

出版信息

Int J Gynaecol Obstet. 2017 Oct;139(1):78-83. doi: 10.1002/ijgo.12240. Epub 2017 Jul 20.

DOI:10.1002/ijgo.12240
PMID:28631355
Abstract

OBJECTIVE

To develop a risk-factor scoring system for the prediction of bleeding during ultrasound-guided dilation and curettage (D&C) for cesarean scar pregnancy (CSP).

METHODS

The retrospective study included patients with a CSP of 31-67 days who underwent transabdominal ultrasonography-guided D&C in 2010-2014. Binary logistic regression analysis was used to identify risk factors for the need of Foley catheter hemostasis. The predictive accuracy of a risk-scoring system based on significant factors was evaluated by receiver operating curve analysis.

RESULTS

Among 82 included patients, 66 (80%) were successfully treated without any complications, whereas 16 (20%) required Foley catheter compression hemostasis. Four patients who received the Foley catheter needed further treatment. A longer pregnancy duration (odds ratio 1.171, 95% confidence interval 1.050-1.305; P=0.004) and a rich blood supply on ultrasonography (odds ratio 3.282, 95% confidence interval 1.441-4.742; P=0.005) were significant risk factors for the need of compression hemostasis. A scoring system based on these two risk factors would have identified 93.8% of patients requiring compression hemostasis if the optimum cutoff score was used.

CONCLUSION

Heavy bleeding during transabdominal ultrasound-guided D&C for CSP is associated with a longer pregnancy duration and a rich blood supply on ultrasonography. The new risk-scoring system can be used to predict bleeding during surgery.

摘要

目的

建立一种风险因素评分系统,用于预测剖宫产瘢痕妊娠(CSP)患者在超声引导下刮宫术(D&C)期间的出血情况。

方法

这项回顾性研究纳入了2010年至2014年期间接受经腹超声引导下刮宫术、妊娠31 - 67天的CSP患者。采用二元逻辑回归分析确定需要使用 Foley 导管止血的风险因素。通过受试者工作特征曲线分析评估基于显著因素的风险评分系统的预测准确性。

结果

在纳入的82例患者中,66例(80%)成功治疗且无任何并发症,而16例(20%)需要使用 Foley 导管压迫止血。4例接受 Foley 导管治疗的患者需要进一步治疗。较长的妊娠时间(比值比1.171,95%置信区间1.050 - 1.305;P = 0.004)和超声检查显示丰富的血供(比值比3.282,95%置信区间1.441 - 4.742;P = 0.005)是需要压迫止血的显著风险因素。如果使用最佳截断分数,基于这两个风险因素的评分系统能够识别出93.8%需要压迫止血的患者。

结论

经腹超声引导下CSP刮宫术期间的大量出血与较长的妊娠时间和超声检查显示丰富的血供有关。新的风险评分系统可用于预测手术期间的出血情况。

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