Mohi Gursimran Kaur, Datta Priya, Chander Jagdish, Das Arjun
Department of Microbiology, Government Medical College Hospital, Chandigarh, India.
Department of Otorhinolaryngology, Government Medical College Hospital, Chandigarh, India.
Indian J Pathol Microbiol. 2017 Apr-Jun;60(2):282-284. doi: 10.4103/0377-4929.208400.
Acute suppurative thyroiditis (AST) is an uncommon condition, in the patients with preexisting thyroid disease or immunosuppression. The most common cause of AST is bacterial, and the most common bacteria are Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, and Klebsiella species. Due to various complications such as septicemia, septic thrombophlebitis, necrotizing mediastinitis, or pericarditis, prompt diagnosis and treatment are the keys to reduce mortality and morbidity. Here, we describe a case of a 40-year-old female with AST caused by Citrobacter freundii. This is the first case report of isolation of this bacterium from AST in the world. It is important to differentiate AST from subacute thyroiditis, which is far more frequent and runs a more prolonged course. Various risk factors which predispose to this condition include structural abnormality in the thyroid gland or thyroid disease and immunocompromised state. The route of infection may be either hematogenous or lymphatic seeding. With the increase in number of immunocompromised patients, the cases of AST will increase.
急性化脓性甲状腺炎(AST)是一种罕见疾病,多见于已有甲状腺疾病或免疫抑制的患者。AST最常见的病因是细菌感染,最常见的细菌是金黄色葡萄球菌、表皮葡萄球菌、大肠杆菌和克雷伯菌属。由于存在败血症、化脓性血栓性静脉炎、坏死性纵隔炎或心包炎等各种并发症,及时诊断和治疗是降低死亡率和发病率的关键。在此,我们描述一例由弗氏柠檬酸杆菌引起的40岁女性AST病例。这是世界上首例从AST中分离出该细菌的病例报告。将AST与亚急性甲状腺炎区分开来很重要,亚急性甲状腺炎更为常见,病程更长。易患此病的各种危险因素包括甲状腺结构异常或甲状腺疾病以及免疫功能低下状态。感染途径可能是血行播散或淋巴播散。随着免疫功能低下患者数量的增加,AST病例将会增多。