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主观睡眠质量与老年人未来跌倒风险的关联:来自 LOHAS 的结果。

Association Between Subjective Sleep Quality and Future Risk of Falls in Older People: Results From LOHAS.

机构信息

Department of Healthcare Epidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan.

Center for Innovative Research for Communities and Clinical Excellence (CIRC2LE), Fukushima Medical University, Fukushima, Japan.

出版信息

J Gerontol A Biol Sci Med Sci. 2018 Aug 10;73(9):1205-1211. doi: 10.1093/gerona/glx123.

Abstract

BACKGROUND

Inadequate sleep is correlated with morbidity and mortality among older adults. However, the longitudinal relationship between subjective sleep quality and risk of falls in the elderly population remains to be clarified.

METHODS

Study participants were from Locomotive Syndrome and Health Outcome in Aizu Cohort Study (LOHAS) sites (1,071 community-dwelling people ≧65 years of age, mean: 71 years). Subjective sleep quality was measured by the Pittsburgh Sleep Quality Index (PSQI). Occurrence of falls (defined as experiencing at least one fall) during the subsequent year was ascertained by a self-reported questionnaire.

RESULTS

Mean global PSQI score was 4.3 (SD 3.2), with 28.9% of participants rating their sleep quality as poor (PSQI > 5). A total of 210 participants (19.6%) fell at least once in the year following sleep examination. Multivariable analysis revealed that participants reporting worse subjective sleep quality had significantly higher odds of experiencing falls during the 1-year follow-up period (adjusted odds ratio [AOR] = 1.50 for each three-point increase in global PSQI score; 95% confidence interval [CI] = 1.20, 1.89). Participants in the highest global PSQI score (PSQI > 5) quartile had significantly increased odds of experiencing falls compared to those in the lowest global score quartile (PSQI < 2; AOR = 2.14; 95% CI = 1.09, 4.22). This association was similarly significant in subgroup analyses for older men and women, nonusers of sleep medication, and those without a history of falls at baseline.

CONCLUSION

Subjective poor sleep quality, as measured by the PSQI, is longitudinally associated with greater risk of experiencing falls in community-dwelling older adults.

摘要

背景

睡眠不足与老年人的发病率和死亡率有关。然而,主观睡眠质量与老年人跌倒风险之间的纵向关系仍需阐明。

方法

研究对象来自 Locomotive Syndrome and Health Outcome in Aizu Cohort Study(LOHAS)研究点(1071 名≥65 岁的社区居住者,平均年龄为 71 岁)。主观睡眠质量通过匹兹堡睡眠质量指数(PSQI)进行测量。通过自我报告的问卷确定随后一年发生的跌倒(定义为至少经历过一次跌倒)情况。

结果

平均全球 PSQI 得分为 4.3(标准差 3.2),28.9%的参与者睡眠质量较差(PSQI>5)。共有 210 名参与者(19.6%)在睡眠检查后的 1 年内至少跌倒过一次。多变量分析显示,报告睡眠质量较差的参与者在 1 年随访期间经历跌倒的可能性显著更高(全球 PSQI 评分每增加 3 分,调整后的优势比[OR]为 1.50;95%置信区间[CI]为 1.20,1.89)。全球 PSQI 得分最高(PSQI>5)四分位数的参与者与全球 PSQI 得分最低(PSQI<2)四分位数的参与者相比,发生跌倒的可能性显著增加(OR=2.14;95%CI=1.09,4.22)。在针对年龄较大的男性和女性、非睡眠药物使用者以及基线时无跌倒史的亚组分析中,这种关联同样显著。

结论

通过 PSQI 测量的主观睡眠质量差与社区居住的老年人群体经历跌倒的风险增加呈纵向相关。

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