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腹主动脉瘤流行病学的变化。

Changes in abdominal aortic aneurysm epidemiology.

作者信息

Lilja Fredrik, Wanhainen Anders, Mani Kevin

机构信息

Section of Vascular Surgery, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

Section of Vascular Surgery, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden -

出版信息

J Cardiovasc Surg (Torino). 2017 Dec;58(6):848-853. doi: 10.23736/S0021-9509.17.10064-9. Epub 2017 Jun 20.

Abstract

The epidemiology and treatment of abdominal aortic aneurysms (AAA) has changed over the past 30 years. This review aims to give the reader an overview of these changes and current trends in AAA epidemiology, management and outcome. In the past decades there have been three changes in AAA management and epidemiology: 1) introduction of endovascular aortic repair (EVAR); 2) population screening; and 3) a markedly reduced prevalence of the disease. These developments have resulted in an increased incidence of intact AAA-repair and reduced incidence of ruptured AAA-repair. Overall, survival after both intact and ruptured AAA repair has improved, much thanks to the broad introduction of EVAR. Additionally, both elective and rupture repair in the elderly population has increased, with octogenarians constituting >20% of intact AAA repairs performed in several countries. International analyses of vascular registries indicate that important variations remain in AAA management and results. The changes in AAA epidemiology and management have led to a situation where most AAAs today are treated with EVAR electively. The incidence of ruptured AAA-repair continues to decrease. These changes are accompanied by improvements in both short- and long-term survival.

摘要

在过去30年里,腹主动脉瘤(AAA)的流行病学及治疗方法发生了变化。本综述旨在让读者了解这些变化以及AAA流行病学、管理和治疗结果的当前趋势。在过去几十年中,AAA的管理和流行病学出现了三个变化:1)血管腔内主动脉修复术(EVAR)的引入;2)人群筛查;3)该疾病的患病率显著降低。这些进展导致完整AAA修复的发生率增加,破裂AAA修复的发生率降低。总体而言,得益于EVAR的广泛应用,完整和破裂AAA修复后的生存率均有所提高。此外,老年人群的择期修复和破裂修复均有所增加,在几个国家,80岁以上老人的完整AAA修复占比超过20%。对血管登记处的国际分析表明,AAA的管理和结果仍存在重要差异。AAA流行病学和管理的变化导致如今大多数AAA采用EVAR进行择期治疗。破裂AAA修复的发生率持续下降。这些变化伴随着短期和长期生存率的提高。

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