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一些色素包衣片剂包衣系统的拉伸各向异性

Tensile anisotropy of some pigmented tablet film coating systems.

作者信息

Okhamafe A O, York P

出版信息

J Pharm Pharmacol. 1985 Jul;37(7):492-3. doi: 10.1111/j.2042-7158.1985.tb03047.x.

Abstract

The tensile properties of representative tablet film coating systems, containing hydroxypropyl methylcellulose alone and in combination with either polyvinyl alcohol, polyethylene glycol 400 and polyethylene glycol 1000 and pigmented with either talc or titanium dioxide, have been investigated. Tensile anisotropy was observed between film samples cut parallel to, and perpendicular to, the direction of rotation of the casting substrate and factors accounting for this phenomenon are presented.

摘要

已对代表性片剂薄膜包衣系统的拉伸性能进行了研究,这些系统单独含有羟丙基甲基纤维素,或与聚乙烯醇、聚乙二醇400和聚乙二醇1000组合,并分别用滑石粉或二氧化钛着色。观察到与浇铸基材旋转方向平行和垂直切割的薄膜样品之间存在拉伸各向异性,并给出了解释这一现象的因素。

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