核糖体随日节律起舞。

Ribosomes Dance to a Daily Rhythm.

机构信息

Molecular Biology of the Cell II, German Cancer Research Center, DKFZ-ZMBH Alliance, Heidelberg, Germany.

出版信息

Trends Biochem Sci. 2017 Aug;42(8):585-587. doi: 10.1016/j.tibs.2017.06.001. Epub 2017 Jun 17.

DOI:10.1016/j.tibs.2017.06.001

Abstract

Sinturel et al. demonstrate that feeding-fasting rhythms and light-dark cycles direct daily changes in liver mass and cell size. These feeding-fasting- and light-dark-driven diurnal fluctuations are controlled by an unconventional mechanism that affects ribosome assembly and protein levels during the active phase.

摘要

辛图雷尔等人证明，摄食-禁食节律和明暗周期指导肝脏质量和细胞大小的日常变化。这些摄食-禁食和明暗驱动的昼夜波动受一种非传统机制的控制，该机制在活动期影响核糖体组装和蛋白质水平。