Vercammen Charlotte, van Wieringen Astrid, Wouters Jan, Francart Tom
a Department of Neurosciences, Research Group Experimental Otorhinolaryngology , KU Leuven-University of Leuven , Leuven , Belgium.
Int J Audiol. 2017 Jul;56(7):464-471. doi: 10.1080/14992027.2017.1288304. Epub 2017 Feb 14.
Binaural processing can be measured objectively as a desynchronisation of phase-locked neural activity to changes in interaural phase differences (IPDs). This was reported in a magnetoencephalography study for 40 Hz amplitude modulated tones. The goal of this study was to measure this desynchronisation using electroencephalography and explore the outcomes for different modulation frequencies.
Auditory steady-state responses (ASSRs) were recorded to pure tones, amplitude modulated at 20, 40 or 80 Hz. IPDs switched between 0 and 180° at fixed time intervals.
Sixteen young listeners with bilateral normal hearing thresholds (≤25 dB HL at 125-8000 Hz) participated in this study.
Significant ASSR phase desynchronisations to IPD changes were detected in 14 out of 16 participants for 40 Hz and in 8, respectively 9, out of 13 participants for 20 and 80 Hz modulators. Desynchronisation and restoration of ASSR phase took place significantly faster for 80 Hz than for 40 and 20 Hz.
ASSR desynchronisation to IPD changes was successfully recorded using electroencephalography. It was feasible for 20, 40 and 80 Hz modulators and could be an objective tool to assess processing of changes in binaural information.
双耳处理可以通过锁相神经活动与双耳相位差（IPD）变化的去同步化进行客观测量。这在一项针对40Hz调幅音的脑磁图研究中得到了报道。本研究的目的是使用脑电图测量这种去同步化，并探索不同调制频率的结果。
记录对20、40或80Hz调幅的纯音的听觉稳态反应（ASSR）。IPD以固定时间间隔在0°和180°之间切换。
16名双侧听力阈值正常（125 - 8000Hz时≤25dB HL）的年轻听众参与了本研究。
16名参与者中有14名在40Hz时检测到对IPD变化有显著的ASSR相位去同步化，13名参与者中有8名和9名分别在20Hz和80Hz调制器时检测到。80Hz时ASSR相位的去同步化和恢复比40Hz和20Hz时明显更快。
使用脑电图成功记录了ASSR对IPD变化的去同步化。对于20、40和80Hz调制器是可行的，并且可能成为评估双耳信息变化处理的一种客观工具。
