Moeen Ahmed M, Safwat Ahmed S, Elderwy Ahmad A, Behnsawy Hosny M, Osman Mahmoud M, Hameed Diaa A
a Department of Urology , Assiut Urology and Nephrology Hospital, Assiut University , Assiut , Egypt.
Scand J Urol. 2017 Apr;51(2):146-151. doi: 10.1080/21681805.2017.1290677. Epub 2017 Feb 23.
The aim of this study was to report the functional outcome after endoscopic management of neobladder complications.
Out of 197 patients who underwent radical cystectomy and orthotopic ileal neobladder reconstruction between 2007 and 2013, 30 patients with delayed postoperative complications were enrolled in this study. Complications were in the form of: eight patients with outflow obstruction, 12 with ureteroenteric stricture, nine with neobladder calculi and one with an isolated recurrent papillary tumor inside the neobladder. Patients were followed up regularly to assess the outcomes of endoscopic treatment.
The mean maximum flow rate and postvoiding residual urine after endoscopic treatment of outflow obstruction were 18.2 ± 3.9 ml/s and 28.7 ± 11 ml, respectively. Ten patients with ureteroenteric stricture showed resolution of hydronephrosis after antegrade dilatation and JJ-stent fixation, with two patients requiring open surgery owing to impassable strictures. Complete clearance of neobladder calculi occurred after endoscopic neocystolithotripsy, with two patients requiring two sessions owing to large calculi. Transurethral resection of the neobladder for isolated tumor recurrence was performed in one patient over two sessions, followed by adjuvant chemoirradiation.
Endourological management of orthotopic neobladder problems is the safest choice. It avoids the difficulties and complications of open surgery and has durable results.
本研究旨在报告内镜治疗新膀胱并发症后的功能结局。
在2007年至2013年间接受根治性膀胱切除术和原位回肠新膀胱重建术的197例患者中,30例术后出现延迟并发症的患者被纳入本研究。并发症形式如下:8例出现流出道梗阻,12例出现输尿管肠吻合口狭窄,9例出现新膀胱结石,1例在新膀胱内出现孤立性复发性乳头状肿瘤。对患者进行定期随访以评估内镜治疗的结果。
内镜治疗流出道梗阻后,平均最大尿流率和排尿后残余尿量分别为18.2±3.9ml/s和28.7±11ml。10例输尿管肠吻合口狭窄患者在顺行扩张和置入双J管固定后肾积水得到缓解,2例因狭窄无法通过而需要开放手术。内镜下新膀胱碎石术后新膀胱结石完全清除,2例因结石较大需要进行两次手术。1例患者分两次进行经尿道新膀胱肿瘤切除术以治疗孤立性肿瘤复发,随后进行辅助放化疗。
原位新膀胱问题的腔内泌尿外科治疗是最安全的选择。它避免了开放手术的困难和并发症,且效果持久。