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经皮肾镜钬激光碎石术后医源性输尿管狭窄的处理:机器人辅助下根治性膀胱切除+原位回肠新膀胱术后并发良性输尿管-肠吻合口狭窄的经皮肾镜下顺行内切开治疗(附 10 例报告)

Transnephrostomic Indocyanine Green-Guided Robotic Ureteral Reimplantation for Benign Ureteroileal Strictures After Robotic Cystectomy and Intracorporeal Neobladder: Step-By-Step Surgical Technique, Perioperative and Functional Outcomes.

机构信息

Department of Urology, "Regina Elena" National Cancer Institute, Rome, Italy.

Department of Urology, Sapienza University, Rome, Italy.

出版信息

J Endourol. 2019 Oct;33(10):823-828. doi: 10.1089/end.2019.0376. Epub 2019 Sep 26.

DOI:10.1089/end.2019.0376
PMID:31397180
Abstract

To describe our surgical technique of robotic ureteroileal reimplantation (RUIR) for ureteroileal anastomosis strictures with the use of near-infrared fluorescence imaging (NIFI) after transnephrostomic antegrade injection of indocyanine green in patients previously treated with robot-assisted radical cystectomy and intracorporeal orthotopic neobladder. From March 2015 to December 2017, 10 consecutive patients underwent RUIR in our tertiary referral center. All patients previously underwent percutaneous nephrostomy and at least one antegrade stenting and stricture dilatation attempt. Clinical data were prospectively collected into our institutional dataset. Both perioperative and functional outcomes were assessed. Median time from robotic cystectomy to ureteroileal anastomosis strictures diagnosis was 5 months (interquartile range [IQR] 2-6). Median stricture length was 1.5 cm (IQR 1-2). Median operative time was 140 minutes (IQR 81-155), and median length of stay was 5 days (IQR 3-9). Two patients experienced Clavien grade 2 complications (urinary tract infection requiring antibiotics and blood transfusion, respectively). One patient underwent ileum resection and anastomosis due to bowel perforation (Clavien IIIb). At a median follow-up of 19 months (IQR 14-39), one patient developed a stricture recurrence. No patient developed worsening of renal function (newly onset chronic kidney disease stage 3b-4). Robotic reimplantation for ureteroileal anastomosis strictures is a safe and highly effective procedure, with a high success rate and excellent perioperative and functional outcomes. NIFI provides an easy guide to identify and progressively dissect the ureter.

摘要

描述我们在机器人辅助根治性膀胱切除术后和体内原位回肠新膀胱患者中经皮肾造瘘管顺行注射吲哚菁绿后,使用近红外荧光成像(NIFI)进行经肾穿刺顺行注射治疗后发生的输尿管 - 回肠吻合口狭窄的机器人输尿管再植入术(RUIR)的手术技术。2015 年 3 月至 2017 年 12 月,我们的三级转诊中心连续 10 例患者接受了 RUIR。所有患者均行经皮肾造瘘术,至少行一次顺行支架置入和狭窄扩张尝试。临床资料前瞻性地纳入我们的机构数据集。评估围手术期和功能结局。从机器人膀胱切除术到诊断输尿管 - 回肠吻合口狭窄的中位时间为 5 个月(四分位距 [IQR] 2-6)。狭窄长度中位数为 1.5cm(IQR 1-2)。手术时间中位数为 140 分钟(IQR 81-155),住院时间中位数为 5 天(IQR 3-9)。2 例患者出现 Clavien 2 级并发症(分别为需要抗生素和输血的尿路感染)。1 例患者因肠穿孔而行回肠切除术和吻合术(Clavien IIIb)。中位随访 19 个月(IQR 14-39),1 例患者出现狭窄复发。无一例患者出现肾功能恶化(新发慢性肾脏病 3b-4 期)。机器人再植入术治疗输尿管 - 回肠吻合口狭窄是一种安全且高效的方法,成功率高,围手术期和功能结局良好。NIFI 提供了一种简便的方法来识别和逐步解剖输尿管。

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