患有非共病和共病形式品行障碍及注意力缺陷多动障碍的青少年的神经认知特征。
Neurocognitive characteristics of youth with noncomorbid and comorbid forms of conduct disorder and attention deficit hyperactivity disorder.
作者信息
Glenn Andrea L, Remmel Rheanna J, Ong Min Yee, Lim Nikki S J, Ang Rebecca P, Threadgill A Hunter, Ryerson Nicole, Raine Adrian, Fung Daniel, Ooi Yoon Phaik
机构信息
Center for the Prevention of Youth Behavior Problems, Department of Psychology, University of Alabama, USA.
Center for the Prevention of Youth Behavior Problems, Department of Psychology, University of Alabama, USA.
出版信息
Compr Psychiatry. 2017 Aug;77:60-70. doi: 10.1016/j.comppsych.2017.06.005. Epub 2017 Jun 8.
OBJECTIVE
Studies investigating neurocognitive deficits in youth with conduct disorder (CD) and attention deficit hyperactivity disorder (ADHD) are often confounded by the high rates of comorbidity between the two.
METHOD
Neurocognitive functioning was examined in three diagnostic groups (ADHD only, CD only, comorbid ADHD and CD) matched by age, sex, IQ, and medication status (n=28-32 per group).
RESULTS
No significant differences emerged between the diagnostic groups on measures of risk-taking or response inhibition. Children with CD performed better on a measure of spatial planning than those with comorbid ADHD and CD, and dimensional analyses in the full sample (n=265) revealed a small association between ADHD symptoms and poorer spatial planning.
CONCLUSION
These results suggest that deficits in spatial planning may be more pronounced in individuals with ADHD, but that the neurocognitive functioning of youth with noncomorbid and comorbid CD and ADHD are largely similar.
目的
研究品行障碍（CD）和注意力缺陷多动障碍（ADHD）青少年的神经认知缺陷时，常因二者之间的高共病率而受到干扰。
方法
对三个诊断组（仅患有ADHD、仅患有CD、同时患有ADHD和CD）进行神经认知功能检查，三组在年龄、性别、智商和用药情况方面相匹配（每组n = 28 - 32）。
结果
在冒险或反应抑制测量方面，诊断组之间未出现显著差异。患有CD的儿童在空间规划测量上的表现优于同时患有ADHD和CD的儿童，全样本（n = 265）的维度分析显示ADHD症状与较差的空间规划之间存在小的关联。
结论
这些结果表明，空间规划缺陷在患有ADHD的个体中可能更为明显，但未患共病以及同时患有CD和ADHD的青少年的神经认知功能在很大程度上是相似的。
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