Department of Molecular Genetics and Microbiology and Center for Virology, Duke University Medical Center, Durham, NC 27710, USA.
Immunity. 2017 Jun 20;46(6):970-972. doi: 10.1016/j.immuni.2017.05.004.
The importance of RNA interference (RNAi) as a mammalian antiviral defense mechanism has been controversial. Qiu et al. (2017) now present data suggesting that the difficulty of detecting RNAi in virus-infected mammalian cells reflects the expression of highly effective viral suppressors of RNAi.
RNA 干扰 (RNAi) 作为一种哺乳动物抗病毒防御机制的重要性一直存在争议。邱等人。(2017) 现在提供的数据表明,在病毒感染的哺乳动物细胞中检测到 RNAi 的困难反映了高度有效的病毒 RNAi 抑制因子的表达。