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Successful conservative management of a permanent pacemaker pocket infection: a less invasive approach.永久性起搏器囊袋感染的成功保守治疗:一种侵入性较小的方法。
BMJ Case Rep. 2017 Jun 20;2017:bcr-2017-220258. doi: 10.1136/bcr-2017-220258.
2
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Pacing Clin Electrophysiol. 2019 Oct;42(10):1340-1346. doi: 10.1111/pace.13787. Epub 2019 Sep 3.
6
Temporary leadless pacing in a patient with severe device infection.
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Conservative management of infected pacemaker and implantable defibrillator sites with a closed antimicrobial irrigation system.采用封闭式抗菌灌洗系统对感染的起搏器和植入式除颤器部位进行保守治疗。
Europace. 2013 Apr;15(4):541-5. doi: 10.1093/europace/eus317. Epub 2012 Sep 26.
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CIED infection with either pocket or systemic infection presentation--complete device removal and long-term antibiotic treatment; long-term outcome.具有囊袋或全身感染表现的心脏植入电子设备(CIED)感染——完全移除设备并进行长期抗生素治疗;长期预后。
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本文引用的文献

1
Conservative therapy for the management of cardiac implantable electronic device infection.心脏植入式电子设备感染的保守治疗
J Arrhythm. 2016 Aug;32(4):293-6. doi: 10.1016/j.joa.2015.09.012. Epub 2015 Nov 19.
2
Guidelines for the diagnosis, prevention and management of implantable cardiac electronic device infection. Report of a joint Working Party project on behalf of the British Society for Antimicrobial Chemotherapy (BSAC, host organization), British Heart Rhythm Society (BHRS), British Cardiovascular Society (BCS), British Heart Valve Society (BHVS) and British Society for Echocardiography (BSE).植入式心脏电子设备感染的诊断、预防和管理指南。英国抗菌化疗学会(BSAC,主办组织)、英国心律学会(BHRS)、英国心血管学会(BCS)、英国心脏瓣膜学会(BHVS)和英国超声心动学会(BSE)代表联合工作组项目的报告。
J Antimicrob Chemother. 2015 Feb;70(2):325-59. doi: 10.1093/jac/dku383. Epub 2014 Oct 29.
3
Conservative treatment of pacemaker pocket infection: is it a viable option?起搏器囊袋感染的保守治疗:这是一个可行的选择吗?
Europace. 2013 Apr;15(4):474-5. doi: 10.1093/europace/eus372. Epub 2012 Nov 23.
4
Conservative management of infected pacemaker and implantable defibrillator sites with a closed antimicrobial irrigation system.采用封闭式抗菌灌洗系统对感染的起搏器和植入式除颤器部位进行保守治疗。
Europace. 2013 Apr;15(4):541-5. doi: 10.1093/europace/eus317. Epub 2012 Sep 26.
5
Therapy of cardiac device pocket infections with vacuum-assisted wound closure-long-term follow-up.采用负压伤口封闭疗法治疗心脏器械囊袋感染——长期随访
Pacing Clin Electrophysiol. 2012 Oct;35(10):1217-21. doi: 10.1111/j.1540-8159.2012.03479.x. Epub 2012 Jul 30.
6
16-year trends in the infection burden for pacemakers and implantable cardioverter-defibrillators in the United States 1993 to 2008.1993 年至 2008 年美国起搏器和植入式心脏复律除颤器感染负担的 16 年趋势。
J Am Coll Cardiol. 2011 Aug 30;58(10):1001-6. doi: 10.1016/j.jacc.2011.04.033.
7
Impact of timing of device removal on mortality in patients with cardiovascular implantable electronic device infections.器械移除时机对心血管植入式电子设备感染患者死亡率的影响。
Heart Rhythm. 2011 Nov;8(11):1678-85. doi: 10.1016/j.hrthm.2011.05.015. Epub 2011 May 27.
8
Complication rates associated with pacemaker or implantable cardioverter-defibrillator generator replacements and upgrade procedures: results from the REPLACE registry.与起搏器或植入式心律转复除颤器(ICD)发生器更换和升级手术相关的并发症发生率:REPLACE 注册研究结果。
Circulation. 2010 Oct 19;122(16):1553-61. doi: 10.1161/CIRCULATIONAHA.110.976076. Epub 2010 Oct 4.
9
Vacuum-assisted wound closure for pacemaker infection.用于起搏器感染的负压伤口闭合术。
Pacing Clin Electrophysiol. 2010 Apr;33(4):426-30. doi: 10.1111/j.1540-8159.2009.02661.x. Epub 2009 Dec 16.
10
Contemporary management of and outcomes from cardiac device related infections.心脏器械相关感染的当代治疗与结局。
Europace. 2010 Jan;12(1):64-70. doi: 10.1093/europace/eup362.

永久性起搏器囊袋感染的成功保守治疗:一种侵入性较小的方法。

Successful conservative management of a permanent pacemaker pocket infection: a less invasive approach.

作者信息

Keeley Alexander James, Hammersley Daniel, Dissanayake Madhava

机构信息

Department of Cardiology, Western Sussex Hospitals NHS Trust, Worthing, UK.

出版信息

BMJ Case Rep. 2017 Jun 20;2017:bcr-2017-220258. doi: 10.1136/bcr-2017-220258.

DOI:10.1136/bcr-2017-220258
PMID:28637845
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5535063/
Abstract

We present a successful conservative management strategy for a frail elderly patient with a cardiac resynchronisation pacemaker who presented with evidence of an pacemaker pocket infection. A device washout and debridement procedure was performed, with reburial of the device in a new prepectoral pocket and creation of a closed-loop continuous antibiotic infusion into the infected pacemaker pocket. This was followed by a 6-week course of ambulatory intravenous antibiotic therapy. This conservative management strategy avoided the need for a more invasive and high-risk full device extraction, which the patient clearly stated he did not wish to have. Up-to-date consensus management guidelines recommend extraction of the entire implanted system in this situation; however, in this case we demonstrate an alternative conservative management option, which may be suitable for frail elderly and comorbid patients or for patients who decline device extraction.

摘要

我们为一名植入心脏再同步起搏器的体弱老年患者制定了一种成功的保守治疗策略,该患者出现了起搏器囊袋感染的迹象。我们进行了设备冲洗和清创手术,将设备重新埋入新的胸前囊袋,并在感染的起搏器囊袋中建立闭环持续抗生素输注。随后进行了为期6周的门诊静脉抗生素治疗。这种保守治疗策略避免了进行更具侵入性和高风险的完全设备取出,患者明确表示他不希望进行这种手术。最新的共识管理指南建议在这种情况下取出整个植入系统;然而,在这个案例中,我们展示了一种替代的保守治疗方案,该方案可能适用于体弱的老年和合并症患者或拒绝取出设备的患者。