Anderson G F, Smey P
Pediatr Clin North Am. 1985 Oct;32(5):1133-49. doi: 10.1016/s0031-3955(16)34898-2.
Vesicoureteral reflux has the potential to cause irreversible renal damage if undiagnosed and untreated. It is important to have a high index of suspicion for the existence of a urinary tract infection in infants and children with any nonspecific generalized illness. Once a UTI is documented, appropriate antibiotic therapy must be started and continued until the urinary tract has been adequately evaluated radiographically. If vesicoureteral reflux is found to exist, appropriate medical or surgical therapy must be instituted to prevent further episodes of pyelonephritis.
如果未被诊断和治疗，膀胱输尿管反流有可能导致不可逆转的肾损伤。对于患有任何非特异性全身性疾病的婴幼儿和儿童，高度怀疑存在尿路感染很重要。一旦记录到尿路感染，必须开始并持续适当的抗生素治疗，直到通过影像学对尿路进行充分评估。如果发现存在膀胱输尿管反流，必须采取适当的药物或手术治疗，以防止肾盂肾炎的进一步发作。
