Yokoyama Tetsuya, Shinozaki Seiji, Arimura Hidenobu, Nakatomi Keita, Wataya Hiroshi
Division of Respiratory Medicine, Department of Internal Medicine, Saiseikai Fukuoka General Hospital, Fukuoka, Japan.
Case Rep Oncol. 2017 Mar 9;10(1):239-243. doi: 10.1159/000463381. eCollection 2017 Jan-Apr.
Various adverse events can occur during antineoplastic therapy. A 67-year-old diabetic woman developed an emphysematous urinary tract infection (UTI) associated with chemoradiotherapy for lung cancer. She had received weekly carboplatin plus paclitaxel with thoracic radiotherapy and developed a fever on day 19. Computed tomography showed a large quantity of gas within the urinary tract. She was therefore diagnosed with emphysematous UTI. Poor diabetes control due to the weekly administration of dexamethasone, an existing urinary tract obstruction, and bone marrow suppression were involved in her serious infection. The potential development of emphysematous UTI during chemoradiotherapy should be considered in at-risk patients.
在抗肿瘤治疗期间可能会发生各种不良事件。一名67岁的糖尿病女性在接受肺癌放化疗时发生了气肿性尿路感染（UTI）。她接受了每周一次的卡铂加紫杉醇联合胸部放疗，在第19天出现发热。计算机断层扫描显示尿路内有大量气体。因此，她被诊断为气肿性UTI。每周使用地塞米松导致糖尿病控制不佳、存在尿路梗阻以及骨髓抑制都与她的严重感染有关。对于高危患者，应考虑放化疗期间气肿性UTI的潜在发生情况。
