Newsum Astrid M, Schinkel Janke, van de Laar Thijs J W, van der Meer Jan T M, Prins Maria
Department of Infectious Diseases Research and Prevention, Public Health Service of Amsterdam.
Department of Internal Medicine, Center for Infection and Immunity Amsterdam (CINIMA), and.
Open Forum Infect Dis. 2017 Jun 16;4(2):ofx090. doi: 10.1093/ofid/ofx090. eCollection 2017 Spring.
We assessed spontaneous clearance in 27 human immunodeficiency virus-infected men who have sex with men (MSM) who seroconverted for hepatitis C virus (HCV). In contrast with a recent estimate of 45.8%, we found a spontaneous clearance rate of 11.1% (95% confidence interval = 2.4-29.2). This finding suggests that treatment deferral to await spontaneous clearance might not be justified for MSM with sexually acquired HCV.
我们评估了27名感染人类免疫缺陷病毒且与男性发生性行为的男性（男男性行为者）的丙型肝炎病毒（HCV）血清转换后的自发清除情况。与最近估计的45.8%相比，我们发现自发清除率为11.1%（95%置信区间 = 2.4 - 29.2）。这一发现表明，对于通过性传播感染HCV的男男性行为者，等待自发清除而推迟治疗可能不合理。
