[Enzyme diagnostic criteria of alcoholism].

Activity of gamma-glutamyltransferase (GGT), aspartate aminotransferase (AsAT) and alanine aminotransferase was determined repeatedly for 5-10 days in the blood serum of patients with Stage I-II alcoholism (n-63) and healthy subjects (n-31). Alcoholism was associated with an elevated activity of GGT and AsAT and its dynamic fluctuations in both directions due to a change in the status of the test subject. It is stated that alcoholism in the considered enzymological manifestations is a pathogenetically unstable state. The authors recommend including the measurement of these enzymes into the complex of measures for alcoholism diagnosis.