使用3-氰基乙烯基咔唑进行超快速光交联诱导的DNA双链双重侵入用于抗原方法。
Double duplex invasion of DNA induced by ultrafast photo-cross-linking using 3-cyanovinylcarbazole for antigene methods.
作者信息
Nakamura Shigetaka, Kawabata Hayato, Fujimoto Kenzo
机构信息
Department of Advanced Science and Technology, Japan Advanced Institute Science and Technology, Asahi-dai, 1-1, Nomi, Ishikawa, Japan.
出版信息
Chem Commun (Camb). 2017 Jul 4;53(54):7616-7619. doi: 10.1039/c7cc01746d.
PMID:28639664
Abstract
In the creation of double duplex formation with genomic DNA, the probe must be able to invade and hybridize to the duplex DNA. We designed new photoresponsive probes containing K and U; these probes have a high double-duplex invasion capability upon photoirradiation.
摘要
在与基因组DNA形成双双链体的过程中，探针必须能够侵入双链DNA并与之杂交。我们设计了含钾和尿嘧啶的新型光响应探针；这些探针在光照射下具有很高的双双链体侵入能力。
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