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MF3蓝细胞血清凝胶的体内美容功效评估。1个月和2个月的测试结果。

Evaluation of the in vivo cosmetic efficacy of the MF3 blue cell serum gel. One- and two-month test results.

作者信息

Tulina Dina, Béguin Alain, Pong Henry, Cabarbas Maria Del Mar, Klokol Dmitry, Chan Mike K S, Wong Michelle B F

机构信息

Nexgen Biopharma Research and Innovations, Zug, Switzerland.

Skin Test Institute, Neuchâtel, Switzerland.

出版信息

J Cosmet Dermatol. 2018 Apr;17(2):193-202. doi: 10.1111/jocd.12363. Epub 2017 Jun 22.

Abstract

INTRODUCTION

Skin is changing over time showing signs of aging: dryness, increase in visual and tactile roughness, decrease in collagen content and stiffness, and eventually formation of deep and surface wrinkles, and fine lines.

METHODS

Eight-week open experimental study was conducted to test efficacy of MF3 Blue Cell Serum Gel. Main criteria to determine product efficacy by following skin biophysical techniques were as follows: skin moisturization, firmness, epidermal and dermal density, skin surface properties and sebum level, reduction in fine lines and wrinkles. Secondary criteria were as follows: participant's opinion during study and product tolerance evaluation. Days 29 and 57 assessments included visual evaluation, skin biophysical techniques, and compliance check. The self-assessment questionnaires completed.

RESULTS

After week 8, obtained results showed very good hydration effect of test product, despite the fact being serum gel. Moisturizing increased continuously during study period. Important increases on skin firmness were observed which are in line with typical anti-aging claims. Dermal density steady improvement noted especially after 4th week of study, and effect on deep skin layers was due to increase in collagen content and stiffness. Sebum regulation process was evidenced. Further significant roughness reduction in skin surface showed decrease or disappearance of fine lines and wrinkles. Products were well tolerated with no adverse events. Most of participants noticed visible improvement and increase in facial radiance, skin smoothness, and overall skin improvement.

CONCLUSION

Twice daily application of MF3 Blue Cell Serum Gel led to significant improvement in skin hydration, firmness, dermal density, sebum regulation, roughness reduction, decrease or disappearance of fine lines and wrinkles.

摘要

引言

皮肤会随着时间变化而出现衰老迹象:干燥、视觉和触觉粗糙度增加、胶原蛋白含量和硬度降低,最终形成深层和表层皱纹以及细纹。

方法

进行了为期八周的开放性实验研究,以测试MF3蓝细胞血清凝胶的功效。通过以下皮肤生物物理技术确定产品功效的主要标准如下:皮肤保湿、紧致度、表皮和真皮密度、皮肤表面特性和皮脂水平、细纹和皱纹的减少。次要标准如下:研究期间参与者的意见和产品耐受性评估。第29天和第57天的评估包括视觉评估、皮肤生物物理技术和依从性检查。完成了自我评估问卷。

结果

八周后,尽管测试产品是血清凝胶,但获得的结果显示其具有非常好的保湿效果。在研究期间,保湿效果持续增强。观察到皮肤紧致度有显著提高,这与典型的抗衰老宣称相符。真皮密度持续改善,尤其是在研究第四周后,对深层皮肤的影响是由于胶原蛋白含量和硬度的增加。皮脂调节过程得到证实。皮肤表面粗糙度进一步显著降低,细纹和皱纹减少或消失。产品耐受性良好,未出现不良事件。大多数参与者注意到面部光泽、皮肤光滑度和整体皮肤状况有明显改善。

结论

每天两次涂抹MF3蓝细胞血清凝胶可显著改善皮肤的水合作用、紧致度、真皮密度、皮脂调节、粗糙度降低以及细纹和皱纹的减少或消失。

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