Bora Emre, Yener Görsev G
1 Department of Psychiatry, Dokuz Eylül University Medical School, Izmir, Turkey.
2 Department of Psychiatry, Melbourne Neuropsychiatry Centre, University of Melbourne and Melbourne Health, Carlton South, Victoria, Australia.
J Geriatr Psychiatry Neurol. 2017 Jul;30(4):206-213. doi: 10.1177/0891988717710337.
Social cognitive abilities are impaired in Alzheimer disease and other dementias. Recent studies suggested that social cognitive abilities might be also impaired in mild cognitive impairment (MCI). Current meta-analysis aimed to summarize available evidence for deficits in theory of mind (ToM) and emotion recognition in MCI. In this meta-analysis of 17 studies, facial emotion recognition and ToM performances of 513 individuals with MCI and 693 healthy controls were compared. Mild cognitive impairment was associated with significant impairments falling in the medium effect sizes range in ToM ( d = 0.63) and facial emotion recognition ( d = 0.58). Among individual emotions, recognition of fear and sadness were particularly impaired. There were no significant between-group differences in recognition of disgust, happiness, and surprise. Social cognitive deficits were more severe in multidomain MCI. There is a need for longitudinal studies investigating the potential role of social cognitive impairment in predicting conversion to dementia.
社交认知能力在阿尔茨海默病和其他痴呆症中会受到损害。最近的研究表明，社交认知能力在轻度认知障碍（MCI）中可能也会受损。当前的荟萃分析旨在总结关于MCI中心智理论（ToM）和情绪识别缺陷的现有证据。在这项对17项研究的荟萃分析中，比较了513名MCI患者和693名健康对照者的面部情绪识别和ToM表现。轻度认知障碍与ToM（d = 0.63）和面部情绪识别（d = 0.58）中处于中等效应量范围的显著损害相关。在个体情绪中，对恐惧和悲伤的识别尤其受损。在对厌恶、快乐和惊讶的识别方面，组间没有显著差异。多领域MCI中的社交认知缺陷更为严重。需要进行纵向研究来调查社交认知障碍在预测向痴呆症转化中的潜在作用。
